ENSG00000142546


Homo sapiens

Features
Gene ID: ENSG00000142546
  
Biological name :NOSIP
  
Synonyms : nitric oxide synthase interacting protein / NOSIP / Q9Y314
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.33
Gene start: 49555711
Gene end: 49590262
  
Corresponding Affymetrix probe sets: 217950_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000471929
Ensembl peptide - ENSP00000471291
Ensembl peptide - ENSP00000472103
Ensembl peptide - ENSP00000473109
Ensembl peptide - ENSP00000343497
Ensembl peptide - ENSP00000468974
Ensembl peptide - ENSP00000470034
Ensembl peptide - ENSP00000470450
NCBI entrez gene - 51070     See in Manteia.
OMIM - 616759
RefSeq - XM_017026852
RefSeq - NM_001270960
RefSeq - NM_015953
RefSeq - XM_005258964
RefSeq - XM_006723235
RefSeq - XM_011527015
RefSeq - XM_011527017
RefSeq - XM_017026851
RefSeq Peptide - NP_001257889
RefSeq Peptide - NP_057037
swissprot - A0A075B797
swissprot - M0QX85
swissprot - M0R1K2
swissprot - M0R1T7
swissprot - M0R3B2
swissprot - Q9Y314
swissprot - A0A075B6F9
Ensembl - ENSG00000142546
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nosipENSDARG00000037958Danio rerio
 NosipENSMUSG00000003421Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003613  U box domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016818  Nitric oxide synthase-interacting protein
 IPR031790  Nitric oxide synthase-interacting protein, zinc-finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043086 negative regulation of catalytic activity IDA
 biological_processGO:0050999 regulation of nitric-oxide synthase activity TAS
 biological_processGO:0051001 negative regulation of nitric-oxide synthase activity IDA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
NOSIP mediated eNOS trafficking


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164867 NOS3 / P29474 / nitric oxide synthase 3  / reaction / complex






 

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contact: otassy@igbmc.fr