ENSG00000143179


Homo sapiens

Features
Gene ID: ENSG00000143179
  
Biological name :UCK2
  
Synonyms : Q9BZX2 / UCK2 / uridine-cytidine kinase 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q24.1
Gene start: 165827531
Gene end: 165911618
  
Corresponding Affymetrix probe sets: 209825_s_at (Human Genome U133 Plus 2.0 Array)   225722_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476692
Ensembl peptide - ENSP00000494961
Ensembl peptide - ENSP00000356853
Ensembl peptide - ENSP00000476327
NCBI entrez gene - 7371     See in Manteia.
OMIM - 609329
RefSeq - NM_012474
RefSeq - XM_011509970
RefSeq - XM_017002236
RefSeq Peptide - NP_036606
swissprot - A0A024R912
swissprot - Q9BZX2
Ensembl - ENSG00000143179
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uck2aENSDARG00000006074Danio rerio
 uck2bENSDARG00000022213Danio rerio
 UCK2ENSGALG00000003510Gallus gallus
 Uck2ENSMUSG00000026558Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UCK1 / Q9HA47 / uridine-cytidine kinase 1ENSG0000013071768
UCKL1 / Q9NWZ5 / uridine-cytidine kinase 1 like 1ENSG0000019827643


Protein motifs (from Interpro)
Interpro ID Name
 IPR000764  Uridine kinase-like
 IPR006083  Phosphoribulokinase/uridine kinase
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR029925  Uridine-cytidine kinase 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006206 pyrimidine nucleobase metabolic process IBA
 biological_processGO:0006238 CMP salvage IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043097 pyrimidine nucleoside salvage IBA
 biological_processGO:0044206 UMP salvage IEA
 biological_processGO:0044211 CTP salvage IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004849 uridine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019206 nucleoside kinase activity EXP


Pathways (from Reactome)
Pathway description
Pyrimidine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143179 UCK2 / Q9BZX2 / uridine-cytidine kinase 2  / complex






 

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