ENSG00000143363


Homo sapiens

Features
Gene ID: ENSG00000143363
  
Biological name :PRUNE1
  
Synonyms : PRUNE1 / prune exopolyphosphatase 1 / Q86TP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q21.3
Gene start: 151008420
Gene end: 151035713
  
Corresponding Affymetrix probe sets: 209586_s_at (Human Genome U133 Plus 2.0 Array)   209599_s_at (Human Genome U133 Plus 2.0 Array)   210988_s_at (Human Genome U133 Plus 2.0 Array)   232490_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387696
Ensembl peptide - ENSP00000271620
Ensembl peptide - ENSP00000357930
Ensembl peptide - ENSP00000357931
Ensembl peptide - ENSP00000392632
Ensembl peptide - ENSP00000357932
Ensembl peptide - ENSP00000357933
NCBI entrez gene - 58497     See in Manteia.
OMIM - 617413
RefSeq - XM_017001957
RefSeq - NM_001303229
RefSeq - NM_001303242
RefSeq - NM_001303243
RefSeq - NM_021222
RefSeq - XM_005245393
RefSeq - XM_011509832
RefSeq - XM_017001955
RefSeq - XM_017001956
RefSeq Peptide - NP_001290171
RefSeq Peptide - NP_001290158
RefSeq Peptide - NP_001290172
RefSeq Peptide - NP_067045
swissprot - Q86TP1
swissprot - Q5SZF2
swissprot - Q5SZG1
Ensembl - ENSG00000143363
  
Related genetic diseases (OMIM): 617481 - Neurodevelopmental disorder with microcephaly, hypotonia, and variable brain anomalies, 617481
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pruneENSDARG00000076246Danio rerio
 PRUNE1ENSGALG00000042220Gallus gallus
 Prune1ENSMUSG00000015711Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001667  DDH domain
 IPR004097  DHHA2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0031113 regulation of microtubule polymerization IMP
 biological_processGO:0050767 regulation of neurogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0004427 inorganic diphosphatase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015631 tubulin binding IDA
 molecular_functionGO:0016462 pyrophosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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