ENSMUSG00000015711


Mus musculus

Features
Gene ID: ENSMUSG00000015711
  
Biological name :Prune1
  
Synonyms : Exopolyphosphatase PRUNE1 / Prune1 / Q8BIW1
  
Possible biological names infered from orthology : prune exopolyphosphatase 1 / Q86TP1
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.1
Gene start: 95253674
Gene end: 95282076
  
Corresponding Affymetrix probe sets: 10500133 (MoGene1.0st)   1433281_at (Mouse Genome 430 2.0 Array)   1434138_at (Mouse Genome 430 2.0 Array)   1457768_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015855
NCBI entrez gene - 229589     See in Manteia.
MGI - MGI:1925152
RefSeq - NM_173347
RefSeq Peptide - NP_775482
swissprot - Q8BIW1
Ensembl - ENSMUSG00000015711
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pruneENSDARG00000076246Danio rerio
 PRUNE1ENSGALG00000042220Gallus gallus
 PRUNE1ENSG00000143363Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001667  DDH domain
 IPR004097  DHHA2 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0031113 regulation of microtubule polymerization IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0004427 inorganic diphosphatase activity IEA
 molecular_functionGO:0015631 tubulin binding IEA
 molecular_functionGO:0016462 pyrophosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001489 decreased startle reflex "greater threshold or less severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, What s Wrong With My Mouse?:ISBN 0-471-31639-3]
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Allelic Composition: Ppp3r2tm1.1(KOMP)Vlcg/Ppp3r2tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Ppp3r2tm1.1(KOMP)Vlcg/Ucd

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Hsp90aa1Tg(Tyr)2396BOve/Hsp90aa1Tg(Tyr)2396BOve
Genetic Background: FVB/N-Hsp90aa1Tg(Tyr)2396BOve

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Prkab1tm1b(KOMP)Wtsi/Prkab1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Prkab1tm1b(KOMP)Wtsi/Orl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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