ENSG00000143556


Homo sapiens

Features
Gene ID: ENSG00000143556
  
Biological name :S100A7
  
Synonyms : P31151 / S100A7 / S100 calcium binding protein A7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q21.3
Gene start: 153457744
Gene end: 153460701
  
Corresponding Affymetrix probe sets: 205916_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357712
Ensembl peptide - ENSP00000357711
NCBI entrez gene - 6278     See in Manteia.
OMIM - 600353
RefSeq - NM_002963
RefSeq Peptide - NP_002954
swissprot - P31151
Ensembl - ENSG00000143556
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86SG5 / S100A7A / S100 calcium binding protein A7AENSG0000018433094
Q5SY68 / S100A7L2 / S100 calcium binding protein A7 like 2ENSG0000019736448


Protein motifs (from Interpro)
Interpro ID Name
 IPR001751  S100/Calbindin-D9k, conserved site
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR013787  S100/CaBP-9k-type, calcium binding, subdomain
 IPR018247  EF-Hand 1, calcium-binding site
 IPR028477  Protein S100-A7
 IPR034325  S-100


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000302 response to reactive oxygen species IDA
 biological_processGO:0001525 angiogenesis NAS
 biological_processGO:0008544 epidermis development TAS
 biological_processGO:0010820 positive regulation of T cell chemotaxis IDA
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0030216 keratinocyte differentiation NAS
 biological_processGO:0032496 response to lipopolysaccharide IEP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045087 innate immune response NAS
 biological_processGO:0050829 defense response to Gram-negative bacterium IMP
 biological_processGO:0051238 sequestering of metal ion IDA
 biological_processGO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IDA
 biological_processGO:0071624 positive regulation of granulocyte chemotaxis IDA
 biological_processGO:0090026 positive regulation of monocyte chemotaxis IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005925 focal adhesion NAS
 cellular_componentGO:0031012 extracellular matrix IDA
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046914 transition metal ion binding IEA
 molecular_functionGO:0050786 RAGE receptor binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Metal sequestration by antimicrobial proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143556 P31151 / S100A7 / S100 calcium binding protein A7  / complex






 

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