ENSG00000143924


Homo sapiens

Features
Gene ID: ENSG00000143924
  
Biological name :EML4
  
Synonyms : echinoderm microtubule associated protein like 4 / EML4 / Q9HC35
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p21
Gene start: 42169350
Gene end: 42332548
  
Corresponding Affymetrix probe sets: 1556732_at (Human Genome U133 Plus 2.0 Array)   220386_s_at (Human Genome U133 Plus 2.0 Array)   223068_at (Human Genome U133 Plus 2.0 Array)   223069_s_at (Human Genome U133 Plus 2.0 Array)   228674_s_at (Human Genome U133 Plus 2.0 Array)   232587_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385059
Ensembl peptide - ENSP00000320663
Ensembl peptide - ENSP00000384939
NCBI entrez gene - 27436     See in Manteia.
OMIM - 607442
RefSeq - XM_006711992
RefSeq - NM_001145076
RefSeq - NM_019063
RefSeq - XM_005264267
RefSeq - XM_005264268
RefSeq - XM_006711991
RefSeq Peptide - NP_001138548
RefSeq Peptide - NP_061936
swissprot - B5MBZ0
swissprot - Q9HC35
Ensembl - ENSG00000143924
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01087623.1ENSDARG00000109443Danio rerio
 EML4ENSGALG00000009915Gallus gallus
 Eml4ENSMUSG00000032624Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EML1 / O00423 / echinoderm microtubule associated protein like 1ENSG0000006662946
EML2 / O95834 / echinoderm microtubule associated protein like 2ENSG0000012574642
EML3 / Q32P44 / echinoderm microtubule associated protein like 3ENSG0000014949941
EML5 / Q05BV3 / echinoderm microtubule associated protein like 5ENSG0000016552127
EML6 / Q6ZMW3 / echinoderm microtubule associated protein like 6ENSG0000021459527
CFAP44 / Q96MT7 / cilia and flagella associated protein 44ENSG0000020653018


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR005108  HELP
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle NAS
 biological_processGO:0007017 microtubule-based process NAS
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IBA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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