ENSG00000125746


Homo sapiens

Features
Gene ID: ENSG00000125746
  
Biological name :EML2
  
Synonyms : echinoderm microtubule associated protein like 2 / EML2 / O95834
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.32
Gene start: 45606994
Gene end: 45645629
  
Corresponding Affymetrix probe sets: 204397_at (Human Genome U133 Plus 2.0 Array)   204398_s_at (Human Genome U133 Plus 2.0 Array)   204399_s_at (Human Genome U133 Plus 2.0 Array)   234021_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468383
Ensembl peptide - ENSP00000468373
Ensembl peptide - ENSP00000468470
Ensembl peptide - ENSP00000468768
Ensembl peptide - ENSP00000245925
Ensembl peptide - ENSP00000382503
Ensembl peptide - ENSP00000442365
Ensembl peptide - ENSP00000464764
Ensembl peptide - ENSP00000464789
Ensembl peptide - ENSP00000464804
Ensembl peptide - ENSP00000464950
Ensembl peptide - ENSP00000465339
Ensembl peptide - ENSP00000465607
Ensembl peptide - ENSP00000465786
Ensembl peptide - ENSP00000465885
Ensembl peptide - ENSP00000465994
Ensembl peptide - ENSP00000466100
Ensembl peptide - ENSP00000467941
Ensembl peptide - ENSP00000468312
Ensembl peptide - ENSP00000468329
NCBI entrez gene - 24139     See in Manteia.
OMIM - 617494
RefSeq - XM_017026551
RefSeq - NM_001193268
RefSeq - NM_001193269
RefSeq - NM_001352051
RefSeq - NM_001352052
RefSeq - NM_001352053
RefSeq - NM_001352054
RefSeq - NM_012155
RefSeq - XM_006723125
RefSeq - XM_006723126
RefSeq - XM_011526694
RefSeq - XM_011526695
RefSeq - XM_011526698
RefSeq - XM_011526700
RefSeq - XM_011526701
RefSeq - XM_017026550
RefSeq Peptide - NP_001338983
RefSeq Peptide - NP_036287
RefSeq Peptide - NP_001338980
RefSeq Peptide - NP_001338981
RefSeq Peptide - NP_001180197
RefSeq Peptide - NP_001180198
RefSeq Peptide - NP_001338982
swissprot - K7EIZ0
swissprot - K7EJV6
swissprot - K7EKG3
swissprot - K7EKU5
swissprot - K7EL23
swissprot - K7ELB2
swissprot - K7ELI8
swissprot - K7EQR0
swissprot - K7ERR2
swissprot - K7ERR9
swissprot - K7ESL7
swissprot - K7ERY9
swissprot - O95834
swissprot - A0A0C4DGQ7
swissprot - C9JRL6
swissprot - K7EII6
swissprot - K7EIK7
swissprot - K7EIM1
Ensembl - ENSG00000125746
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eml2ENSDARG00000008808Danio rerio
 Eml2ENSMUSG00000040811Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EML1 / O00423 / echinoderm microtubule associated protein like 1ENSG0000006662960
EML4 / Q9HC35 / echinoderm microtubule associated protein like 4ENSG0000014392449
EML3 / Q32P44 / echinoderm microtubule associated protein like 3ENSG0000014949940
EML5 / Q05BV3 / echinoderm microtubule associated protein like 5ENSG0000016552131
EML6 / Q6ZMW3 / echinoderm microtubule associated protein like 6ENSG0000021459530
CFAP44 / Q96MT7 / cilia and flagella associated protein 44ENSG0000020653019


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR005108  HELP
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007601 visual perception TAS
 biological_processGO:0007605 sensory perception of sound TAS
 biological_processGO:0010968 regulation of microtubule nucleation IDA
 biological_processGO:0031115 negative regulation of microtubule polymerization IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005875 microtubule associated complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0072686 mitotic spindle IDA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0008022 protein C-terminus binding IEA
 molecular_functionGO:0015631 tubulin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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