ENSMUSG00000040811


Mus musculus

Features
Gene ID: ENSMUSG00000040811
  
Biological name :Eml2
  
Synonyms : Eml2 / Mus musculus echinoderm microtubule associated protein like 2 (Eml2), transcript variant 3, mRNA. / Q7TNG5
  
Possible biological names infered from orthology : echinoderm microtubule associated protein like 2 / O95834
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A3
Gene start: 19176421
Gene end: 19206482
  
Corresponding Affymetrix probe sets: 10550605 (MoGene1.0st)   10550625 (MoGene1.0st)   1428173_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112491
Ensembl peptide - ENSMUSP00000112447
Ensembl peptide - ENSMUSP00000115466
Ensembl peptide - ENSMUSP00000146239
Ensembl peptide - ENSMUSP00000146046
Ensembl peptide - ENSMUSP00000037654
NCBI entrez gene - 72205     See in Manteia.
MGI - MGI:1919455
RefSeq - XM_017312323
RefSeq - NM_001162996
RefSeq - NM_001347582
RefSeq - NM_028153
RefSeq - XM_011250713
RefSeq - XM_011250714
RefSeq - XM_011250715
RefSeq - XM_011250718
RefSeq - XM_011250719
RefSeq Peptide - NP_082429
RefSeq Peptide - NP_001156468
RefSeq Peptide - NP_001334511
swissprot - E9QK48
swissprot - A0A0U1RPM7
swissprot - Q7TNG5
swissprot - D6RGM3
swissprot - A0A0U1RQ42
Ensembl - ENSMUSG00000040811
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eml2ENSDARG00000008808Danio rerio
 EML2ENSG00000125746Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Eml1 / Q05BC3 / Echinoderm microtubule-associated protein-like 1 / O00423*ENSMUSG0000005807061
Eml4 / echinoderm microtubule-associated protein-like 4 isoform 4 / Q9HC35* / echinoderm microtubule associated protein like 4*ENSMUSG0000003262449
Eml3 / Q8VC03 / Echinoderm microtubule-associated protein-like 3 / Q32P44*ENSMUSG0000007164745
Eml5 / Q8BQM8 / Echinoderm microtubule-associated protein-like 5 / Q05BV3*ENSMUSG0000005116631
Eml6 / Q5SQM0 / Echinoderm microtubule-associated protein-like 6 / Q6ZMW3*ENSMUSG0000004407231
Cfap44 / cilia and flagella associated protein 44 / Q96MT7*ENSMUSG0000007155019


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR005108  HELP
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010968 regulation of microtubule nucleation ISO
 biological_processGO:0031115 negative regulation of microtubule polymerization ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0072686 mitotic spindle ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008017 microtubule binding IBA
 molecular_functionGO:0015631 tubulin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001415 increased exploration in new environment "greater amount of time spent investigating new location" [J:28825]
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Allelic Composition: Pofut2tm2.2Bch/Pofut2tm2.2Bch
Genetic Background: B6.Cg-Pofut2tm2.2Bch

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pofut2tm2.2Bch/Pofut2tm2.2Bch
Genetic Background: B6.Cg-Pofut2tm2.2Bch

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr