ENSG00000144339


Homo sapiens

Features
Gene ID: ENSG00000144339
  
Biological name :TMEFF2
  
Synonyms : Q9UIK5 / TMEFF2 / transmembrane protein with EGF like and two follistatin like domains 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q32.3
Gene start: 191949043
Gene end: 192195709
  
Corresponding Affymetrix probe sets: 223557_s_at (Human Genome U133 Plus 2.0 Array)   224321_at (Human Genome U133 Plus 2.0 Array)   233910_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000272771
Ensembl peptide - ENSP00000376128
Ensembl peptide - ENSP00000386871
NCBI entrez gene - 23671     See in Manteia.
OMIM - 605734
RefSeq - XM_017003740
RefSeq - NM_001305134
RefSeq - NM_001305145
RefSeq - NM_016192
RefSeq - XM_011510890
RefSeq - XM_017003739
RefSeq Peptide - NP_001292063
RefSeq Peptide - NP_001292074
RefSeq Peptide - NP_057276
swissprot - Q9UIK5
Ensembl - ENSG00000144339
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmeff2aENSDARG00000051824Danio rerio
 tmeff2bENSDARG00000058699Danio rerio
 TMEFF2ENSGALG00000007759Gallus gallus
 Q9QYM9ENSMUSG00000026109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8IYR6 / TMEFF1 / transmembrane protein with EGF like and two follistatin like domains 1ENSG0000024169747
MSANTD3-TMEFF1 / MSANTD3-TMEFF1 readthroughENSG0000025134945


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR002350  Kazal domain
 IPR013032  EGF-like, conserved site
 IPR036058  Kazal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0044319 wound healing, spreading of cells IDA
 biological_processGO:0045720 negative regulation of integrin biosynthetic process IMP
 biological_processGO:0051497 negative regulation of stress fiber assembly IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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