ENSG00000144746


Homo sapiens

Features
Gene ID: ENSG00000144746
  
Biological name :ARL6IP5
  
Synonyms : ADP ribosylation factor like GTPase 6 interacting protein 5 / ARL6IP5 / O75915
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p14.1
Gene start: 69084944
Gene end: 69106066
  
Corresponding Affymetrix probe sets: 200760_s_at (Human Genome U133 Plus 2.0 Array)   200761_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000273258
Ensembl peptide - ENSP00000420138
Ensembl peptide - ENSP00000419374
Ensembl peptide - ENSP00000419021
NCBI entrez gene - 10550     See in Manteia.
OMIM - 605709
RefSeq - NM_006407
RefSeq Peptide - NP_006398
swissprot - F8WF90
swissprot - C9JQU6
swissprot - O75915
swissprot - A0A024R371
swissprot - F8WF33
Ensembl - ENSG00000144746
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arl6ip5aENSDARG00000077044Danio rerio
 arl6ip5bENSDARG00000016238Danio rerio
 Q5F433ENSGALG00000038904Gallus gallus
 Q8R5J9ENSMUSG00000035199Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRAF2 / O60831 / PRA1 domain family member 2ENSG0000024327940


Protein motifs (from Interpro)
Interpro ID Name
 IPR004895  Prenylated rab acceptor PRA1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002037 negative regulation of L-glutamate import across plasma membrane ISS
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress IDA
 biological_processGO:0010917 negative regulation of mitochondrial membrane potential IMP
 biological_processGO:0015813 L-glutamate transmembrane transport ISS
 biological_processGO:0032874 positive regulation of stress-activated MAPK cascade IMP
 biological_processGO:0043065 positive regulation of apoptotic process IMP
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Glutamate Neurotransmitter Release Cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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