ENSG00000144867


Homo sapiens

Features
Gene ID: ENSG00000144867
  
Biological name :SRPRB
  
Synonyms : Q9Y5M8 / SRPRB / SRP receptor beta subunit
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q22.1
Gene start: 133784033
Gene end: 133825772
  
Corresponding Affymetrix probe sets: 218140_x_at (Human Genome U133 Plus 2.0 Array)   222532_at (Human Genome U133 Plus 2.0 Array)   227737_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000417096
Ensembl peptide - ENSP00000418401
Ensembl peptide - ENSP00000417316
NCBI entrez gene - 58477     See in Manteia.
OMIM - 616883
RefSeq - NM_021203
RefSeq Peptide - NP_067026
swissprot - H7C4H2
swissprot - C9J5Z8
swissprot - Q549N5
swissprot - Q9Y5M8
Ensembl - ENSG00000144867
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 srprbENSDARG00000030949Danio rerio
 SRPRBENSGALG00000026302Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019009  Signal recognition particle receptor, beta subunit
 IPR024156  Small GTPase superfamily, ARF type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005785 signal recognition particle receptor complex IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005881 cytoplasmic microtubule IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005047 signal recognition particle binding IBA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
SRP-dependent cotranslational protein targeting to membrane
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000182934 SRPRA / P08240 / SRP receptor alpha subunit  / complex






 

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contact: otassy@igbmc.fr