ENSG00000144895


Homo sapiens

Features
Gene ID: ENSG00000144895
  
Biological name :EIF2A
  
Synonyms : EIF2A / eukaryotic translation initiation factor 2A / Q9BY44
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q25.1
Gene start: 150546678
Gene end: 150584242
  
Corresponding Affymetrix probe sets: 223015_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000420537
Ensembl peptide - ENSP00000420495
Ensembl peptide - ENSP00000420611
Ensembl peptide - ENSP00000273435
Ensembl peptide - ENSP00000385292
Ensembl peptide - ENSP00000417229
Ensembl peptide - ENSP00000417575
Ensembl peptide - ENSP00000418698
Ensembl peptide - ENSP00000419456
Ensembl peptide - ENSP00000420493
NCBI entrez gene - 83939     See in Manteia.
OMIM - 609234
RefSeq - XM_011513224
RefSeq - NM_001319043
RefSeq - NM_001319044
RefSeq - NM_001319045
RefSeq - NM_001319046
RefSeq - NM_032025
RefSeq Peptide - NP_114414
RefSeq Peptide - NP_001305974
RefSeq Peptide - NP_001305975
RefSeq Peptide - NP_001305972
RefSeq Peptide - NP_001305973
swissprot - F8WF18
swissprot - H7C5Q3
swissprot - H7C5R5
swissprot - H7C5Q4
swissprot - Q9BY44
swissprot - C9IZE1
swissprot - F8WAE5
swissprot - F8WAT3
Ensembl - ENSG00000144895
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif2aENSDARG00000101061Danio rerio
 EIF2AENSGALG00000010401Gallus gallus
 Eif2aENSMUSG00000027810Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR011387  Translation initiation factor 2A
 IPR013979  Translation initiation factor, beta propellor-like domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0032933 SREBP signaling pathway IEA
 biological_processGO:0042255 ribosome assembly IMP
 biological_processGO:1990928 response to amino acid starvation IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005850 eukaryotic translation initiation factor 2 complex IDA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IBA
 cellular_componentGO:0072562 blood microparticle HDA
 molecular_functionGO:0000049 tRNA binding IMP
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0043022 ribosome binding IMP
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr