ENSMUSG00000027810


Mus musculus

Features
Gene ID: ENSMUSG00000027810
  
Biological name :Eif2a
  
Synonyms : Eif2a / Eukaryotic translation initiation factor 2A Eukaryotic translation initiation factor 2A, N-terminally processed / Q8BJW6
  
Possible biological names infered from orthology : eukaryotic translation initiation factor 2A / Q9BY44
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: D
Gene start: 58525821
Gene end: 58557501
  
Corresponding Affymetrix probe sets: 10492205 (MoGene1.0st)   1434452_x_at (Mouse Genome 430 2.0 Array)   1445563_at (Mouse Genome 430 2.0 Array)   1460575_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029387
Ensembl peptide - ENSMUSP00000122375
Ensembl peptide - ENSMUSP00000121236
Ensembl peptide - ENSMUSP00000120901
NCBI entrez gene - 229317     See in Manteia.
MGI - MGI:1098684
RefSeq - XM_006501321
RefSeq - NM_001005509
RefSeq Peptide - NP_001005509
swissprot - D6RFN2
swissprot - D6RGA6
swissprot - Q8BJW6
swissprot - D3YZZ6
Ensembl - ENSMUSG00000027810
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif2aENSDARG00000101061Danio rerio
 EIF2AENSGALG00000010401Gallus gallus
 EIF2AENSG00000144895Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR011387  Translation initiation factor 2A
 IPR013979  Translation initiation factor, beta propellor-like domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IDA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006417 regulation of translation ISO
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0009967 positive regulation of signal transduction IDA
 biological_processGO:0032933 SREBP signaling pathway IDA
 biological_processGO:0042255 ribosome assembly IEA
 biological_processGO:1990928 response to amino acid starvation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005850 eukaryotic translation initiation factor 2 complex IEA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IBA
 molecular_functionGO:0000049 tRNA binding IEA
 molecular_functionGO:0003729 mRNA binding IBA
 molecular_functionGO:0003743 translation initiation factor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0043022 ribosome binding IEA
 molecular_functionGO:0045296 cadherin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cfap157tm1b(EUCOMM)Hmgu/Cfap157tm1b(EUCOMM)Hmgu
Genetic Background: involves: C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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