ENSG00000145088


Homo sapiens

Features
Gene ID: ENSG00000145088
  
Biological name :EAF2
  
Synonyms : EAF2 / ELL associated factor 2 / Q96CJ1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q13.33
Gene start: 121835183
Gene end: 121886526
  
Corresponding Affymetrix probe sets: 1568672_at (Human Genome U133 Plus 2.0 Array)   1568673_s_at (Human Genome U133 Plus 2.0 Array)   219551_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419552
Ensembl peptide - ENSP00000273668
Ensembl peptide - ENSP00000410708
Ensembl peptide - ENSP00000418374
NCBI entrez gene - 55840     See in Manteia.
OMIM - 607659
RefSeq - XM_017006863
RefSeq - NM_001320041
RefSeq - NM_018456
RefSeq - XM_005247618
RefSeq - XM_017006861
RefSeq Peptide - NP_001306970
RefSeq Peptide - NP_060926
swissprot - F8WCI9
swissprot - F8WF04
swissprot - Q96CJ1
swissprot - B4DWJ3
Ensembl - ENSG00000145088
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eaf2ENSDARG00000010432Danio rerio
 EAF2ENSGALG00000011657Gallus gallus
 Eaf2ENSMUSG00000022838Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EAF1 / Q96JC9 / ELL associated factor 1ENSG0000014459754


Protein motifs (from Interpro)
Interpro ID Name
 IPR019194  Transcription elognation factor Eaf, N-terminal
 IPR027093  EAF family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II TAS
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter TAS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 biological_processGO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0008023 transcription elongation factor complex IDA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0032783 ELL-EAF complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr