ENSDARG00000010432


Danio rerio

Features
Gene ID: ENSDARG00000010432
  
Biological name :eaf2
  
Synonyms : eaf2 / ELL associated factor 2
  
Possible biological names infered from orthology : Q91ZD6 / Q96CJ1
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 23003208
Gene end: 23007941
  
Corresponding Affymetrix probe sets: Dr.199.1.A1_at (Zebrafish Array)   NM_001002162_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000005794
NCBI entrez gene - 415252     See in Manteia.
RefSeq - NM_001002162
RefSeq Peptide - NP_001002162
swissprot - Q6IQU8
ZFIN ID - ZDB-GENE-040625-179
Ensembl - ENSDARG00000010432
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EAF2ENSGALG00000011657Gallus gallus
 EAF2ENSG00000145088Homo sapiens
 Eaf2ENSMUSG00000022838Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eaf1 / ELL associated factor 1 / Q96JC9* / Q9D4C5*ENSDARG0000007079554


Protein motifs (from Interpro)
Interpro ID Name
 IPR019194  Transcription elognation factor Eaf, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development IGI
 biological_processGO:0014812 muscle cell migration IGI
 biological_processGO:0030111 regulation of Wnt signaling pathway IGI
 biological_processGO:0031016 pancreas development IGI
 biological_processGO:0042074 cell migration involved in gastrulation IGI
 biological_processGO:0060028 convergent extension involved in axis elongation IMP
 biological_processGO:0060029 convergent extension involved in organogenesis IGI
 cellular_componentGO:0032783 ELL-EAF complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IPI
 molecular_functionGO:0070016 armadillo repeat domain binding IDA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000003 adaxial cell adaxial cell position , abnormal
Show

 ZFA:0000060 prechordal plate prechordal plate mislocalised posteriorly , abnormal
Show

 ZFA:0000091 axial chorda mesoderm axial chorda mesoderm decreased length , abnormal
Show

 ZFA:0000107 eye eye fused with eye , abnormal
Show

 ZFA:0000132 neural plate neural plate increased width , abnormal
Show

 ZFA:0000279 segmental plate segmental plate decreased length , abnormal
Show

 ZFA:0000416 presumptive endoderm presumptive endoderm increased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
Show

 ZFA:0001120 neuroectoderm neuroectoderm anterior region decreased size , abnormal
neuroectoderm anterior region increased size , abnormal
Show

 ZFA:0001377 presumptive mesoderm presumptive mesoderm increased width , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr