ENSDARG00000070795


Danio rerio

Features
Gene ID: ENSDARG00000070795
  
Biological name :eaf1
  
Synonyms : eaf1 / ELL associated factor 1
  
Possible biological names infered from orthology : Q96JC9 / Q9D4C5
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 6944311
Gene end: 6955545
  
Corresponding Affymetrix probe sets: Dr.3524.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000095027
Ensembl peptide - ENSDARP00000113981
NCBI entrez gene - 415205     See in Manteia.
swissprot - E9QHY6
swissprot - Q6IQD2
ZFIN ID - ZDB-GENE-040625-109
Ensembl - ENSDARG00000070795
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EAF1ENSGALG00000033379Gallus gallus
 EAF1ENSG00000144597Homo sapiens
 Eaf1ENSMUSG00000021890Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eaf2 / ELL associated factor 2 / Q91ZD6* / Q96CJ1*ENSDARG0000001043255


Protein motifs (from Interpro)
Interpro ID Name
 IPR019194  Transcription elognation factor Eaf, N-terminal
 IPR027093  EAF family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007507 heart development IGI
 biological_processGO:0014812 muscle cell migration IGI
 biological_processGO:0030111 regulation of Wnt signaling pathway IGI
 biological_processGO:0031016 pancreas development IGI
 biological_processGO:0042074 cell migration involved in gastrulation IGI
 biological_processGO:0060028 convergent extension involved in axis elongation IMP
 biological_processGO:0060029 convergent extension involved in organogenesis IGI
 biological_processGO:0060215 primitive hemopoiesis IMP
 biological_processGO:0060216 definitive hemopoiesis IMP
 cellular_componentGO:0032783 ELL-EAF complex IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IPI
 molecular_functionGO:0070016 armadillo repeat domain binding IDA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
RNA Polymerase II Pre-transcription Events
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000003 adaxial cell adaxial cell position , abnormal
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 ZFA:0000091 axial chorda mesoderm axial chorda mesoderm decreased length , abnormal
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 ZFA:0000132 neural plate neural plate increased width , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
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 ZFA:0001120 neuroectoderm neuroectoderm anterior region increased size , abnormal
neuroectoderm anterior region decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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