ENSG00000145113


Homo sapiens

Features
Gene ID: ENSG00000145113
  
Biological name :MUC4
  
Synonyms : MUC4 / mucin 4, cell surface associated / Q99102
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: q29
Gene start: 195746765
Gene end: 195812277
  
Corresponding Affymetrix probe sets: 1561785_at (Human Genome U133 Plus 2.0 Array)   204895_x_at (Human Genome U133 Plus 2.0 Array)   217109_at (Human Genome U133 Plus 2.0 Array)   217110_s_at (Human Genome U133 Plus 2.0 Array)   235055_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000407750
Ensembl peptide - ENSP00000417397
Ensembl peptide - ENSP00000420439
Ensembl peptide - ENSP00000420243
Ensembl peptide - ENSP00000419989
Ensembl peptide - ENSP00000419798
Ensembl peptide - ENSP00000418306
Ensembl peptide - ENSP00000417757
Ensembl peptide - ENSP00000417722
Ensembl peptide - ENSP00000417657
Ensembl peptide - ENSP00000417498
Ensembl peptide - ENSP00000304207
Ensembl peptide - ENSP00000310528
Ensembl peptide - ENSP00000338109
Ensembl peptide - ENSP00000345378
Ensembl peptide - ENSP00000376208
Ensembl peptide - ENSP00000389780
NCBI entrez gene - 4585     See in Manteia.
OMIM - 158372
RefSeq - NM_018406
RefSeq - NM_138297
RefSeq - NM_004532
RefSeq Peptide - NP_004523
RefSeq Peptide - NP_060876
RefSeq Peptide - NP_612154
swissprot - E7EQT2
swissprot - E7EQG8
swissprot - E7ENC5
swissprot - H0Y2Y1
swissprot - H7BXN7
swissprot - H7BZI3
swissprot - E9PDY6
swissprot - Q99102
swissprot - E7EWN1
swissprot - E7EW47
swissprot - E7EUL9
swissprot - E7ETT5
swissprot - E7ERK0
Ensembl - ENSG00000145113
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-105b23.6ENSDARG00000087190Danio rerio
 ENSGALG00000032657Gallus gallus
 Muc4ENSMUSG00000079620Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SUSD2 / Q9UGT4 / sushi domain containing 2ENSG000000999943


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001846  von Willebrand factor, type D domain
 IPR003886  NIDO domain
 IPR005533  AMOP domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002223 stimulatory C-type lectin receptor signaling pathway TAS
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0030277 maintenance of gastrointestinal epithelium IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005796 Golgi lumen TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031982 vesicle HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005176 ErbB-2 class receptor binding TAS
 molecular_functionGO:0030197 extracellular matrix constituent, lubricant activity NAS


Pathways (from Reactome)
Pathway description
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)
Defective GALNT12 causes colorectal cancer 1 (CRCS1)
Dectin-2 family
O-linked glycosylation of mucins
Termination of O-glycan biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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