ENSG00000145194


Homo sapiens

Features
Gene ID: ENSG00000145194
  
Biological name :ECE2
  
Synonyms : ECE2 / endothelin converting enzyme 2 / O60344
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q27.1
Gene start: 184276011
Gene end: 184293031
  
Corresponding Affymetrix probe sets: 1555306_a_at (Human Genome U133 Plus 2.0 Array)   206728_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352052
Ensembl peptide - ENSP00000350066
Ensembl peptide - ENSP00000392467
Ensembl peptide - ENSP00000398444
Ensembl peptide - ENSP00000385846
NCBI entrez gene - 9718     See in Manteia.
OMIM - 610145
RefSeq - NM_001037324
RefSeq - NM_001100121
RefSeq - NM_001100120
RefSeq Peptide - NP_001032401
RefSeq Peptide - NP_001093591
RefSeq Peptide - NP_001093590
swissprot - O60344
swissprot - F8WCL9
swissprot - H0Y5G8
Ensembl - ENSG00000145194
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ECE2ENSDARG00000102142Danio rerio
 ENSGALG00000006272Gallus gallus
 Ece2ENSMUSG00000115293Mus musculus
 Ece2ENSMUSG00000022842Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O60344 / EEF1AKMT4-ECE2 / EEF1AKMT4-ECE2 readthroughENSG0000028491790
ECE1 / P42892 / endothelin converting enzyme 1ENSG0000011729859
MMEL1 / Q495T6 / membrane metalloendopeptidase like 1ENSG0000014260636
ECEL1 / O95672 / endothelin converting enzyme like 1ENSG0000017155135
MME / P08473 / membrane metalloendopeptidaseENSG0000019654932
PHEX / P78562 / phosphate regulating endopeptidase homolog X-linkedENSG0000010217430
KEL / P23276 / Kell blood group, metallo-endopeptidaseENSG0000019799327


Protein motifs (from Interpro)
Interpro ID Name
 IPR000718  Peptidase M13
 IPR008753  Peptidase M13, N-terminal domain
 IPR018497  Peptidase M13, C-terminal domain
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR029733  Endothelin-converting enzyme


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0016486 peptide hormone processing IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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