ENSG00000145495


Homo sapiens

Features
Gene ID: ENSG00000145495
  
Biological name :MARCH6
  
Synonyms : MARCH6 / membrane associated ring-CH-type finger 6 / O60337
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p15.2
Gene start: 10353703
Gene end: 10440388
  
Corresponding Affymetrix probe sets: 201736_s_at (Human Genome U133 Plus 2.0 Array)   201737_s_at (Human Genome U133 Plus 2.0 Array)   212498_at (Human Genome U133 Plus 2.0 Array)   215422_at (Human Genome U133 Plus 2.0 Array)   215423_at (Human Genome U133 Plus 2.0 Array)   215512_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425930
Ensembl peptide - ENSP00000424512
Ensembl peptide - ENSP00000426000
Ensembl peptide - ENSP00000491579
Ensembl peptide - ENSP00000274140
Ensembl peptide - ENSP00000414643
NCBI entrez gene - 10299     See in Manteia.
OMIM - 613297
RefSeq - XM_011513937
RefSeq - NM_001270660
RefSeq - NM_001270661
RefSeq - NM_005885
RefSeq - XM_011513932
RefSeq - XM_011513934
RefSeq - XM_011513936
RefSeq Peptide - NP_005876
RefSeq Peptide - NP_001257589
RefSeq Peptide - NP_001257590
swissprot - D6RHY7
swissprot - O60337
swissprot - A0A0B4J206
Ensembl - ENSG00000145495
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 march6ENSDARG00000076066Danio rerio
 MARCH6ENSGALG00000035699Gallus gallus
 March6ENSMUSG00000039100Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011016  Zinc finger, RING-CH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010498 proteasomal protein catabolic process IDA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0036503 ERAD pathway TAS
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:1904380 endoplasmic reticulum mannose trimming TAS
 cellular_componentGO:0000835 ER ubiquitin ligase complex IC
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IDA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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