ENSG00000145725


Homo sapiens

Features
Gene ID: ENSG00000145725
  
Biological name :PPIP5K2
  
Synonyms : diphosphoinositol pentakisphosphate kinase 2 / O43314 / PPIP5K2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q21.1
Gene start: 103120149
Gene end: 103212799
  
Corresponding Affymetrix probe sets: 203253_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467099
Ensembl peptide - ENSP00000465165
Ensembl peptide - ENSP00000467529
Ensembl peptide - ENSP00000486357
Ensembl peptide - ENSP00000482907
Ensembl peptide - ENSP00000480381
Ensembl peptide - ENSP00000313070
Ensembl peptide - ENSP00000351126
Ensembl peptide - ENSP00000416016
Ensembl peptide - ENSP00000421513
Ensembl peptide - ENSP00000422525
Ensembl peptide - ENSP00000424535
Ensembl peptide - ENSP00000424948
NCBI entrez gene - 23262     See in Manteia.
OMIM - 611648
RefSeq - XM_017009275
RefSeq - XM_005277536
RefSeq - XM_005277538
RefSeq - XM_005277539
RefSeq - XM_005277541
RefSeq - XM_006714576
RefSeq - XM_006714577
RefSeq - XM_011543290
RefSeq - XM_017009269
RefSeq - XM_017009270
RefSeq - XM_017009271
RefSeq - XM_017009272
RefSeq - XM_017009273
RefSeq - XM_017009274
RefSeq - NM_001276277
RefSeq - NM_001281471
RefSeq - NM_015216
RefSeq - XM_005271935
RefSeq - XM_005271936
RefSeq - XM_005271938
RefSeq - XM_005277534
RefSeq - XM_005277535
RefSeq Peptide - NP_056031
RefSeq Peptide - NP_001263206
RefSeq Peptide - NP_001268400
swissprot - H0Y9M0
swissprot - H0Y9S9
swissprot - K7EJG8
swissprot - D6RFG4
swissprot - K7EPT7
swissprot - O43314
swissprot - A0A087WWN8
swissprot - K7ENU7
swissprot - D6RBU4
swissprot - A0A087WZV0
Ensembl - ENSG00000145725
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppip5k2ENSDARG00000078441Danio rerio
 PPIP5K2ENSGALG00000015264Gallus gallus
 Q6ZQB6ENSMUSG00000040648Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PFW1 / PPIP5K1 / diphosphoinositol pentakisphosphate kinase 1ENSG0000016878164


Protein motifs (from Interpro)
Interpro ID Name
 IPR000560  Histidine phosphatase superfamily, clade-2
 IPR029033  Histidine phosphatase superfamily
 IPR033379  Histidine acid phosphatase active site
 IPR037446  Histidine acid phosphatase, VIP1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006020 inositol metabolic process ISS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032958 inositol phosphate biosynthetic process IBA
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity ISS
 molecular_functionGO:0000828 inositol hexakisphosphate kinase activity IEA
 molecular_functionGO:0000829 inositol heptakisphosphate kinase activity IEA
 molecular_functionGO:0000832 inositol hexakisphosphate 5-kinase activity ISS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0033857 diphosphoinositol-pentakisphosphate kinase activity IEA
 molecular_functionGO:0052723 inositol hexakisphosphate 1-kinase activity IEA
 molecular_functionGO:0052724 inositol hexakisphosphate 3-kinase activity IEA
 molecular_functionGO:0102092 5-diphosphoinositol pentakisphosphate 3-kinase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of pyrophosphates in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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