ENSG00000168781


Homo sapiens

Features
Gene ID: ENSG00000168781
  
Biological name :PPIP5K1
  
Synonyms : diphosphoinositol pentakisphosphate kinase 1 / PPIP5K1 / Q6PFW1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q15.3
Gene start: 43533462
Gene end: 43590253
  
Corresponding Affymetrix probe sets: 1555255_a_at (Human Genome U133 Plus 2.0 Array)   204578_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000405200
Ensembl peptide - ENSP00000405106
Ensembl peptide - ENSP00000407704
Ensembl peptide - ENSP00000496290
Ensembl peptide - ENSP00000415349
Ensembl peptide - ENSP00000410563
Ensembl peptide - ENSP00000308773
Ensembl peptide - ENSP00000334779
Ensembl peptide - ENSP00000353253
Ensembl peptide - ENSP00000353446
Ensembl peptide - ENSP00000371303
Ensembl peptide - ENSP00000371309
Ensembl peptide - ENSP00000380129
Ensembl peptide - ENSP00000387999
Ensembl peptide - ENSP00000390657
Ensembl peptide - ENSP00000400887
NCBI entrez gene - 9677     See in Manteia.
OMIM - 610979
RefSeq - XM_017022760
RefSeq - XM_017022739
RefSeq - XM_017022740
RefSeq - XM_017022741
RefSeq - XM_017022742
RefSeq - XM_017022743
RefSeq - XM_017022744
RefSeq - XM_017022745
RefSeq - XM_017022746
RefSeq - XM_017022747
RefSeq - XM_017022748
RefSeq - XM_017022749
RefSeq - XM_017022750
RefSeq - XM_017022751
RefSeq - XM_017022752
RefSeq - XM_017022753
RefSeq - XM_017022754
RefSeq - XM_017022755
RefSeq - XM_017022756
RefSeq - XM_017022757
RefSeq - XM_017022758
RefSeq - XM_017022759
RefSeq - NM_001130858
RefSeq - NM_001130859
RefSeq - NM_001190214
RefSeq - NM_001354382
RefSeq - NM_001354383
RefSeq - NM_001354384
RefSeq - NM_001354385
RefSeq - NM_001354386
RefSeq - NM_001354390
RefSeq - NM_001354391
RefSeq - NM_001354392
RefSeq - NM_014659
RefSeq - XM_005254803
RefSeq - XM_005254804
RefSeq - XM_006720786
RefSeq - XM_011522249
RefSeq - XM_011522250
RefSeq - XM_011522252
RefSeq - XM_011522254
RefSeq - XM_011522258
RefSeq - XM_011522259
RefSeq - XM_017022735
RefSeq - XM_017022736
RefSeq - XM_017022737
RefSeq - XM_017022738
RefSeq Peptide - NP_001124331
RefSeq Peptide - NP_001341312
RefSeq Peptide - NP_001341313
RefSeq Peptide - NP_001341314
RefSeq Peptide - NP_001341315
RefSeq Peptide - NP_001341319
RefSeq Peptide - NP_001341320
RefSeq Peptide - NP_001341321
RefSeq Peptide - NP_055474
RefSeq Peptide - NP_001124330
RefSeq Peptide - NP_001177143
RefSeq Peptide - NP_001341311
swissprot - C9J5E6
swissprot - C9J490
swissprot - F8W9A8
swissprot - H0Y3Y5
swissprot - H7C398
swissprot - H7C436
swissprot - C9JZX6
swissprot - Q6PFW1
swissprot - B7WPL9
Ensembl - ENSG00000168781
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppip5k1aENSDARG00000076143Danio rerio
 ppip5k1bENSDARG00000073909Danio rerio
 PPIP5K1ENSGALG00000008385Gallus gallus
 A2ARP1ENSMUSG00000033526Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O43314 / PPIP5K2 / diphosphoinositol pentakisphosphate kinase 2ENSG0000014572557


Protein motifs (from Interpro)
Interpro ID Name
 IPR000560  Histidine phosphatase superfamily, clade-2
 IPR029033  Histidine phosphatase superfamily
 IPR033379  Histidine acid phosphatase active site
 IPR037446  Histidine acid phosphatase, VIP1 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006020 inositol metabolic process IDA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0032958 inositol phosphate biosynthetic process IBA
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity IDA
 molecular_functionGO:0000828 inositol hexakisphosphate kinase activity TAS
 molecular_functionGO:0000829 inositol heptakisphosphate kinase activity TAS
 molecular_functionGO:0000832 inositol hexakisphosphate 5-kinase activity IEA
 molecular_functionGO:0005524 ATP binding ISS
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0033857 diphosphoinositol-pentakisphosphate kinase activity IEA
 molecular_functionGO:0052723 inositol hexakisphosphate 1-kinase activity IEA
 molecular_functionGO:0052724 inositol hexakisphosphate 3-kinase activity IEA
 molecular_functionGO:0102092 5-diphosphoinositol pentakisphosphate 3-kinase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of pyrophosphates in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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