ENSG00000145740


Homo sapiens

Features
Gene ID: ENSG00000145740
  
Biological name :SLC30A5
  
Synonyms : Q8TAD4 / SLC30A5 / solute carrier family 30 member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q13.1
Gene start: 69093646
Gene end: 69131069
  
Corresponding Affymetrix probe sets: 1555334_s_at (Human Genome U133 Plus 2.0 Array)   218989_x_at (Human Genome U133 Plus 2.0 Array)   220181_x_at (Human Genome U133 Plus 2.0 Array)   232432_s_at (Human Genome U133 Plus 2.0 Array)   243166_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427111
Ensembl peptide - ENSP00000426751
Ensembl peptide - ENSP00000483105
Ensembl peptide - ENSP00000370241
Ensembl peptide - ENSP00000379836
Ensembl peptide - ENSP00000421251
Ensembl peptide - ENSP00000423078
NCBI entrez gene - 64924     See in Manteia.
OMIM - 607819
RefSeq - XM_017009749
RefSeq - NM_001251969
RefSeq - NM_022902
RefSeq - NM_024055
RefSeq - XM_005248569
RefSeq - XM_006714672
RefSeq Peptide - NP_001238898
RefSeq Peptide - NP_075053
RefSeq Peptide - NP_076960
swissprot - H0Y957
swissprot - H0YAH4
swissprot - Q8TAD4
swissprot - Q9BY48
swissprot - D6REM2
Ensembl - ENSG00000145740
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q6DG36ENSDARG00000051921Danio rerio
 Q5ZLF4ENSGALG00000014787Gallus gallus
 Q8R4H9ENSMUSG00000021629Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8NEW0 / SLC30A7 / solute carrier family 30 member 7ENSG0000016269520
Q6NXT4 / SLC30A6 / solute carrier family 30 member 6ENSG0000015268312


Protein motifs (from Interpro)
Interpro ID Name
 IPR002524  Cation efflux protein
 IPR027469  Cation efflux transmembrane domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006824 cobalt ion transport IDA
 biological_processGO:0006829 zinc ion transport IEA
 biological_processGO:0006882 cellular zinc ion homeostasis IDA
 biological_processGO:0010043 response to zinc ion IDA
 biological_processGO:0010155 regulation of proton transport NAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061088 regulation of sequestering of zinc ion IBA
 biological_processGO:0071577 zinc ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0030667 secretory granule membrane TAS
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity IDA
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0008324 cation transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Insulin processing
Zinc efflux and compartmentalization by the SLC30 family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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