ENSG00000145934


Homo sapiens

Features
Gene ID: ENSG00000145934
  
Biological name :TENM2
  
Synonyms : Q9NT68 / teneurin transmembrane protein 2 / TENM2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q34
Gene start: 167284799
Gene end: 168264157
  
Corresponding Affymetrix probe sets: 231867_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427874
Ensembl peptide - ENSP00000428964
Ensembl peptide - ENSP00000429430
NCBI entrez gene - 57451     See in Manteia.
OMIM - 610119
RefSeq - XM_017009669
RefSeq - XM_017009664
RefSeq - XM_017009665
RefSeq - XM_017009666
RefSeq - XM_017009667
RefSeq - XM_017009668
RefSeq - NM_001080428
RefSeq - NM_001122679
RefSeq - XM_005265950
RefSeq - XM_005265952
RefSeq - XM_006714897
RefSeq - XM_011534604
RefSeq - XM_017009660
RefSeq - XM_017009661
RefSeq - XM_017009662
RefSeq - XM_017009663
RefSeq Peptide - NP_001073897
RefSeq Peptide - NP_001116151
swissprot - G3V106
swissprot - Q9NT68
swissprot - F8VNQ3
Ensembl - ENSG00000145934
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-12m10.1ENSDARG00000011171Danio rerio
 si:ch211-166i24.1ENSDARG00000090676Danio rerio
 TENM2ENSDARG00000037122Danio rerio
 TENM2ENSGALG00000001768Gallus gallus
 Tenm2ENSMUSG00000049336Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TENM3 / Q9P273 / teneurin transmembrane protein 3ENSG0000021833669
TENM4 / Q6N022 / teneurin transmembrane protein 4ENSG0000014925665
TENM1 / Q9UKZ4 / teneurin transmembrane protein 1ENSG0000000969458
VWDE / Q8N2E2 / von Willebrand factor D and EGF domainsENSG000001465307
WIF1 / Q9Y5W5 / WNT inhibitory factor 1ENSG000001560763


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR006530  YD repeat
 IPR008969  Carboxypeptidase-like, regulatory domain superfamily
 IPR009471  Teneurin intracellular, N-terminal
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR011044  Quinoprotein amine dehydrogenase, beta chain-like
 IPR013032  EGF-like, conserved site
 IPR022385  Rhs repeat-associated core
 IPR027689  Teneurin-2/3
 IPR028916  Tox-GHH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0000902 cell morphogenesis IBA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0048666 neuron development IBA
 biological_processGO:0051491 positive regulation of filopodium assembly ISS
 biological_processGO:0097264 self proteolysis IEA
 biological_processGO:0098609 cell-cell adhesion ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016605 PML body ISS
 cellular_componentGO:0030054 cell junction ISS
 cellular_componentGO:0030175 filopodium ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043197 dendritic spine ISS
 cellular_componentGO:0045202 synapse ISS
 cellular_componentGO:0045211 postsynaptic membrane ISS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IBA
 molecular_functionGO:0050839 cell adhesion molecule binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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