ENSG00000156076


Homo sapiens

Features
Gene ID: ENSG00000156076
  
Biological name :WIF1
  
Synonyms : Q9Y5W5 / WIF1 / WNT inhibitory factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q14.3
Gene start: 65050626
Gene end: 65121566
  
Corresponding Affymetrix probe sets: 204712_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000439024
Ensembl peptide - ENSP00000442063
Ensembl peptide - ENSP00000286574
NCBI entrez gene - 11197     See in Manteia.
OMIM - 605186
RefSeq - NM_007191
RefSeq Peptide - NP_009122
swissprot - Q9Y5W5
swissprot - F5H8A3
swissprot - H0YFK7
Ensembl - ENSG00000156076
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wif1ENSDARG00000005541Danio rerio
 WIF1ENSGALG00000039209Gallus gallus
 Wif1ENSMUSG00000020218Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
VWDE / Q8N2E2 / von Willebrand factor D and EGF domainsENSG0000014653031
TENM1 / Q9UKZ4 / teneurin transmembrane protein 1ENSG0000000969421
TENM3 / Q9P273 / teneurin transmembrane protein 3ENSG0000021833621
TENM4 / Q6N022 / teneurin transmembrane protein 4ENSG0000014925620
TENM2 / Q9NT68 / teneurin transmembrane protein 2ENSG0000014593417


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR003306  WIF domain
 IPR013032  EGF-like, conserved site
 IPR013111  EGF-like domain, extracellular
 IPR013309  Wnt inhibitory factor (WIF)-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway NAS
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017147 Wnt-protein binding NAS


Pathways (from Reactome)
Pathway description
TCF dependent signaling in response to WNT
Negative regulation of TCF-dependent signaling by WNT ligand antagonists


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114251 WNT5A / P41221 / Wnt family member 5A  / reaction / complex
 ENSG00000154342 WNT3A / P56704 / Wnt family member 3A  / reaction / complex
 ENSG00000143816 WNT9A / O14904 / Wnt family member 9A  / complex / reaction
 ENSG00000162552 WNT4 / P56705 / Wnt family member 4  / complex / reaction






 

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