ENSMUSG00000020218


Mus musculus

Features
Gene ID: ENSMUSG00000020218
  
Biological name :Wif1
  
Synonyms : Q9WUA1 / Wif1 / Wnt inhibitory factor 1
  
Possible biological names infered from orthology : Q9Y5W5
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: D2
Gene start: 121033960
Gene end: 121100650
  
Corresponding Affymetrix probe sets: 10366653 (MoGene1.0st)   1425425_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020439
Ensembl peptide - ENSMUSP00000135486
NCBI entrez gene - 24117     See in Manteia.
MGI - MGI:1344332
RefSeq - NM_011915
RefSeq Peptide - NP_036045
swissprot - H3BKQ8
swissprot - Q3TYU1
swissprot - Q9WUA1
Ensembl - ENSMUSG00000020218
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wif1ENSDARG00000005541Danio rerio
 WIF1ENSGALG00000039209Gallus gallus
 WIF1ENSG00000156076Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tenm3 / teneurin transmembrane protein 3 / Q9P273*ENSMUSG0000003156122
Tenm4 / Q3UHK6 / Teneurin-4 / Q6N022* / teneurin transmembrane protein 4*ENSMUSG0000004807821
Tenm1 / Q9WTS4 / teneurin transmembrane protein 1 / Q9UKZ4*ENSMUSG0000001615021
Tenm2 / teneurin-2 isoform 2 / Q9NT68* / teneurin transmembrane protein 2*ENSMUSG0000004933619
Vwde / Q6DFV8 / von Willebrand factor D and EGF domains / Q8N2E2*ENSMUSG000000796798


Protein motifs (from Interpro)
Interpro ID Name
 IPR000742  EGF-like domain
 IPR003306  WIF domain
 IPR013032  EGF-like, conserved site
 IPR013309  Wnt inhibitory factor (WIF)-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0030178 negative regulation of Wnt signaling pathway ISO
 biological_processGO:0045600 positive regulation of fat cell differentiation IDA
 cellular_componentGO:0005576 extracellular region TAS
 molecular_functionGO:0017147 Wnt-protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002021 increased incidence of induced tumors "higher than normal frequency of tumor incidence induced by a carcinogen or mutagen" [J:44427]
Show

Allelic Composition: Rbm15tm1.1(MAL)Dgg/Rbm15tm1.1(MAL)Dgg
Genetic Background: B6.129-Rbm15tm1.1(MAL)Dgg

 MP:0002032 sarcoma "connective tissue neoplasm associated with the proliferation of mesodermal cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
Show

Allelic Composition: Rbm15tm1.1(MAL)Dgg/Rbm15tm1.1(MAL)Dgg
Genetic Background: B6.129-Rbm15tm1.1(MAL)Dgg

 MP:0003789 osteosarcoma "malignant neoplasm derived from bone" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Rbm15tm1.1(MAL)Dgg/Rbm15tm1.1(MAL)Dgg
Genetic Background: B6.129-Rbm15tm1.1(MAL)Dgg

 MP:0009763 increased sensitivity to induced morbidity/mortality "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rbm15tm1.1(MAL)Dgg/Rbm15tm1.1(MAL)Dgg
Genetic Background: B6.129-Rbm15tm1.1(MAL)Dgg

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000000126 Wnt9a / Q8R5M2 / wingless-type MMTV integration site family, member 9A / O14904* / Wnt family member 9A*  / complex / reaction
 ENSMUSG00000009900 Wnt3a / P27467 / wingless-type MMTV integration site family, member 3A / P56704* / Wnt family member 3A*  / reaction / complex
 ENSMUSG00000021994 Wnt5a / P22725 / wingless-type MMTV integration site family, member 5A / P41221* / Wnt family member 5A*  / reaction / complex
 ENSMUSG00000036856 Wnt4 / P22724 / wingless-type MMTV integration site family, member 4 / P56705* / Wnt family member 4*  / complex / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr