ENSG00000146151


Homo sapiens

Features
Gene ID: ENSG00000146151
  
Biological name :HMGCLL1
  
Synonyms : 3-hydroxymethyl-3-methylglutaryl-CoA lyase like 1 / HMGCLL1 / Q8TB92
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p12.1
Gene start: 55434369
Gene end: 55579214
  
Corresponding Affymetrix probe sets: 1554872_a_at (Human Genome U133 Plus 2.0 Array)   232305_at (Human Genome U133 Plus 2.0 Array)   233576_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381654
Ensembl peptide - ENSP00000412924
Ensembl peptide - ENSP00000426054
Ensembl peptide - ENSP00000424309
Ensembl peptide - ENSP00000274901
Ensembl peptide - ENSP00000309737
Ensembl peptide - ENSP00000359887
Ensembl peptide - ENSP00000359889
NCBI entrez gene - 54511     See in Manteia.
RefSeq - XM_011514700
RefSeq - NM_001042406
RefSeq - NM_001287741
RefSeq - NM_001287746
RefSeq - NM_001287753
RefSeq - NM_019036
RefSeq Peptide - NP_061909
RefSeq Peptide - NP_001035865
RefSeq Peptide - NP_001274670
RefSeq Peptide - NP_001274675
RefSeq Peptide - NP_001274682
swissprot - D6RHJ2
swissprot - Q8TB92
swissprot - B7Z212
swissprot - B7Z4D4
swissprot - G5E9S9
Ensembl - ENSG00000146151
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 A8WG57ENSDARG00000088740Danio rerio
 HMGCLL1ENSGALG00000016294Gallus gallus
 Q8JZS7ENSMUSG00000007908Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HMGCL / P35914 / 3-hydroxymethyl-3-methylglutaryl-CoA lyaseENSG0000011730558


Protein motifs (from Interpro)
Interpro ID Name
 IPR000891  Pyruvate carboxyltransferase
 IPR013785  Aldolase-type TIM barrel
 IPR030021  HMG-CoA lyase-like1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046951 ketone body biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004419 hydroxymethylglutaryl-CoA lyase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding TAS


Pathways (from Reactome)
Pathway description
Synthesis of Ketone Bodies


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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