ENSDARG00000088740


Danio rerio

Features
Gene ID: ENSDARG00000088740
  
Biological name :hmgcll1
  
Synonyms : 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 / A8WG57 / hmgcll1
  
Possible biological names infered from orthology : 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic / Q8JZS7 / Q8TB92
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 1928361
Gene end: 1981727
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000105104
Ensembl peptide - ENSDARP00000133158
NCBI entrez gene - 571388     See in Manteia.
RefSeq - NM_001110400
RefSeq Peptide - NP_001103870
swissprot - A8WG57
swissprot - A0A0R4IDR6
swissprot - F1QQ84
ZFIN ID - ZDB-GENE-080220-15
Ensembl - ENSDARG00000088740
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HMGCLL1ENSGALG00000016294Gallus gallus
 Q8TB92ENSG00000146151Homo sapiens
 Q8JZS7ENSMUSG00000007908Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hmgcl / 3-hydroxymethyl-3-methylglutaryl-CoA lyase / P35914* / P38060* / Hydroxymethylglutaryl-CoA lyase, mitochondrial *ENSDARG0000002122066


Protein motifs (from Interpro)
Interpro ID Name
 IPR000891  Pyruvate carboxyltransferase
 IPR013785  Aldolase-type TIM barrel
 IPR030021  HMG-CoA lyase-like1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046951 ketone body biosynthetic process ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISS
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol ISS
 cellular_componentGO:0016020 membrane ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004419 hydroxymethylglutaryl-CoA lyase activity ISS
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0046872 metal ion binding ISS


Pathways (from Reactome)
Pathway description
Synthesis of Ketone Bodies


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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