ENSDARG00000021220


Danio rerio

Features
Gene ID: ENSDARG00000021220
  
Biological name :hmgcl
  
Synonyms : 3-hydroxymethyl-3-methylglutaryl-CoA lyase / hmgcl
  
Possible biological names infered from orthology : Hydroxymethylglutaryl-CoA lyase, mitochondrial / P35914 / P38060
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 24855384
Gene end: 24866964
  
Corresponding Affymetrix probe sets: Dr.7938.1.S1_at (Zebrafish Array)   NM_201215_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000026028
Ensembl peptide - ENSDARP00000145263
Ensembl peptide - ENSDARP00000151601
NCBI entrez gene - 394190     See in Manteia.
RefSeq - NM_201215
RefSeq Peptide - NP_957509
swissprot - F1QTF0
ZFIN ID - ZDB-GENE-040426-958
Ensembl - ENSDARG00000021220
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HMGCLENSGALG00000004057Gallus gallus
 HMGCLENSG00000117305Homo sapiens
 HmgclENSMUSG00000028672Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A8WG57 / hmgcll1 / 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 / Q8JZS7* / Q8TB92* / 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic *ENSDARG0000008874065


Protein motifs (from Interpro)
Interpro ID Name
 IPR000138  Hydroxymethylglutaryl-CoA lyase, active site
 IPR000891  Pyruvate carboxyltransferase
 IPR013785  Aldolase-type TIM barrel
 IPR030020  Hydroxymethylglutaryl-CoA lyase, mitochondrial


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004419 hydroxymethylglutaryl-CoA lyase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of Ketone Bodies
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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