ENSG00000146618


Homo sapiens

Features
Gene ID: ENSG00000146618
  
Biological name :FERD3L
  
Synonyms : Fer3 like bHLH transcription factor / FERD3L / Q96RJ6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p21.1
Gene start: 19144782
Gene end: 19145421
  
Corresponding Affymetrix probe sets: 1553517_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000275461
NCBI entrez gene - 222894     See in Manteia.
OMIM - 617578
RefSeq - NM_152898
RefSeq Peptide - NP_690862
swissprot - Q96RJ6
Ensembl - ENSG00000146618
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ferd3lENSDARG00000092160Danio rerio
 FERD3LENSGALG00000010862Gallus gallus
 Ferd3lENSMUSG00000046518Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTF1A / Q7RTS3 / pancreas specific transcription factor, 1aENSG0000016826731


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0033504 floor plate development IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0048468 cell development IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 cellular_componentGO:0005634 nucleus ISS
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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