ENSG00000146676


Homo sapiens

Features
Gene ID: ENSG00000146676
  
Biological name :PURB
  
Synonyms : PURB / purine rich element binding protein B / Q96QR8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p13
Gene start: 44876293
Gene end: 44885361
  
Corresponding Affymetrix probe sets: 225120_at (Human Genome U133 Plus 2.0 Array)   226762_at (Human Genome U133 Plus 2.0 Array)   227718_at (Human Genome U133 Plus 2.0 Array)   228467_at (Human Genome U133 Plus 2.0 Array)   235711_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379051
NCBI entrez gene - 5814     See in Manteia.
OMIM - 608887
RefSeq - NM_033224
RefSeq Peptide - NP_150093
swissprot - Q96QR8
Ensembl - ENSG00000146676
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 purbaENSDARG00000068822Danio rerio
 purbbENSDARG00000103546Danio rerio
 PurbENSMUSG00000094483Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PURA / Q00577 / purine rich element binding protein AENSG0000018512967
PURG / Q9UJV8 / purine rich element binding protein GENSG0000017273352


Protein motifs (from Interpro)
Interpro ID Name
 IPR006628  Purine-rich element binding protein family
 IPR030499  Purine-rich element-binding protein beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0045637 regulation of myeloid cell differentiation NAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005662 DNA replication factor A complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0046332 SMAD binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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