ENSG00000147677


Homo sapiens

Features
Gene ID: ENSG00000147677
  
Biological name :EIF3H
  
Synonyms : EIF3H / eukaryotic translation initiation factor 3 subunit H / O15372
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.11
Gene start: 116642130
Gene end: 116766925
  
Corresponding Affymetrix probe sets: 201592_at (Human Genome U133 Plus 2.0 Array)   230570_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427908
Ensembl peptide - ENSP00000276682
Ensembl peptide - ENSP00000482724
Ensembl peptide - ENSP00000430926
Ensembl peptide - ENSP00000429931
Ensembl peptide - ENSP00000429884
Ensembl peptide - ENSP00000428885
Ensembl peptide - ENSP00000428669
Ensembl peptide - ENSP00000428195
NCBI entrez gene - 8667     See in Manteia.
OMIM - 603912
RefSeq - NM_003756
RefSeq Peptide - NP_003747
swissprot - E5RH59
swissprot - E5RGU4
swissprot - E5RFW7
swissprot - E5RFH0
swissprot - B3KS98
swissprot - A0A087WZK9
swissprot - O15372
swissprot - E5RJT0
swissprot - Q6IB98
swissprot - E5RHC7
Ensembl - ENSG00000147677
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FO704771.1ENSDARG00000116963Danio rerio
 EIF3HENSGALG00000040522Gallus gallus
 Eif3hENSMUSG00000022312Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000555  JAB1/MPN/MOV34 metalloenzyme domain
 IPR027524  Eukaryotic translation initiation factor 3 subunit H
 IPR037518  MPN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001732 formation of cytoplasmic translation initiation complex IEA
 biological_processGO:0002183 cytoplasmic translational initiation IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation IEA
 biological_processGO:0006446 regulation of translational initiation TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005852 eukaryotic translation initiation factor 3 complex IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016282 eukaryotic 43S preinitiation complex IEA
 cellular_componentGO:0033290 eukaryotic 48S preinitiation complex IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003743 translation initiation factor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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