ENSG00000147799


Homo sapiens

Features
Gene ID: ENSG00000147799
  
Biological name :ARHGAP39
  
Synonyms : ARHGAP39 / Q9C0H5 / Rho GTPase activating protein 39
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.3
Gene start: 144529179
Gene end: 144605816
  
Corresponding Affymetrix probe sets: 227876_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000276826
Ensembl peptide - ENSP00000366522
NCBI entrez gene - 80728     See in Manteia.
OMIM - 615880
RefSeq - XM_017013871
RefSeq - NM_001308207
RefSeq - NM_001308208
RefSeq - NM_025251
RefSeq - XM_011517308
RefSeq - XM_011517309
RefSeq - XM_011517312
RefSeq - XM_017013870
RefSeq Peptide - NP_001295137
RefSeq Peptide - NP_079527
RefSeq Peptide - NP_001295136
swissprot - Q9C0H5
Ensembl - ENSG00000147799
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgap39ENSDARG00000100007Danio rerio
 ENSGALG00000039346Gallus gallus
 Arhgap39ENSMUSG00000033697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000198  Rho GTPase-activating protein domain
 IPR000857  MyTH4 domain
 IPR001202  WW domain
 IPR008936  Rho GTPase activation protein
 IPR036020  WW domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Inactivation of CDC42 and RAC1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136238 RAC1 / P63000 / Rac family small GTPase 1  / reaction
 ENSG00000145147 SLIT2 / O94813 / slit guidance ligand 2  / complex / reaction
 ENSG00000169855 ROBO1 / Q9Y6N7 / roundabout guidance receptor 1  / reaction / complex






 

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