ENSG00000147813


Homo sapiens

Features
Gene ID: ENSG00000147813
  
Biological name :NAPRT
  
Synonyms : NAPRT / nicotinate phosphoribosyltransferase / Q6XQN6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.3
Gene start: 143574785
Gene end: 143578649
  
Corresponding Affymetrix probe sets: 226707_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433245
Ensembl peptide - ENSP00000405670
Ensembl peptide - ENSP00000437102
Ensembl peptide - ENSP00000478911
Ensembl peptide - ENSP00000341136
Ensembl peptide - ENSP00000390949
Ensembl peptide - ENSP00000401508
NCBI entrez gene - 93100     See in Manteia.
OMIM - 611552
RefSeq - XM_017013980
RefSeq - NM_001286829
RefSeq - NM_145201
RefSeq - XM_017013975
RefSeq - XM_017013976
RefSeq - XM_017013977
RefSeq - XM_017013978
RefSeq - XM_017013979
RefSeq Peptide - NP_660202
RefSeq Peptide - NP_001273758
swissprot - G5E977
swissprot - H0YDA6
swissprot - H0YF31
swissprot - Q6XQN6
swissprot - A0A087WUT5
swissprot - C9J8U2
Ensembl - ENSG00000147813
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 naprtENSDARG00000027930Danio rerio
 NAPRTENSGALG00000038175Gallus gallus
 NaprtENSMUSG00000022574Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006405  Nicotinate phosphoribosyltransferase pncB-type
 IPR007229  Nicotinate phosphoribosyltransferase family
 IPR036068  Nicotinate phosphoribosyltransferase-like, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0009435 NAD biosynthetic process IEA
 biological_processGO:0019358 nicotinate nucleotide salvage IEA
 biological_processGO:0019363 pyridine nucleotide biosynthetic process IEA
 biological_processGO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0035578 azurophil granule lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity IEA
 molecular_functionGO:0004516 nicotinate phosphoribosyltransferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000147813 NAPRT / Q6XQN6 / nicotinate phosphoribosyltransferase  / complex






 

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