ENSG00000147854


Homo sapiens

Features
Gene ID: ENSG00000147854
  
Biological name :UHRF2
  
Synonyms : Q96PU4 / ubiquitin like with PHD and ring finger domains 2 / UHRF2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: p24.1
Gene start: 6413151
Gene end: 6507054
  
Corresponding Affymetrix probe sets: 225610_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000276893
Ensembl peptide - ENSP00000434182
Ensembl peptide - ENSP00000399217
Ensembl peptide - ENSP00000370778
NCBI entrez gene - 115426     See in Manteia.
OMIM - 615211
RefSeq - XM_017014253
RefSeq - XM_017014254
RefSeq - XM_011517705
RefSeq - NM_152896
RefSeq - XM_011517704
RefSeq Peptide - NP_690856
swissprot - Q96PU4
swissprot - A0A0A0MSQ3
swissprot - B1AL33
Ensembl - ENSG00000147854
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 UHRF2ENSGALG00000015052Gallus gallus
 Uhrf2ENSMUSG00000024817Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
UHRF1 / Q96T88 / ubiquitin like with PHD and ring finger domains 1ENSG0000027604354


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR001841  Zinc finger, RING-type
 IPR001965  Zinc finger, PHD-type
 IPR003105  SRA-YDG
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014722  Ribosomal protein L2, domain 2
 IPR015947  PUA-like superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR019787  Zinc finger, PHD-finger
 IPR021991  UHRF1, tandem tudor domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR036987  SRA-YDG superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008283 cell proliferation IEP
 biological_processGO:0010216 maintenance of DNA methylation IBA
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0030154 cell differentiation IEP
 biological_processGO:0051726 regulation of cell cycle TAS
 biological_processGO:0051865 protein autoubiquitination IDA
 biological_processGO:0071158 positive regulation of cell cycle arrest IDA
 biological_processGO:0090308 regulation of methylation-dependent chromatin silencing IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005720 nuclear heterochromatin IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042393 histone binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
SUMOylation of transcription cofactors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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