ENSG00000148411


Homo sapiens

Features
Gene ID: ENSG00000148411
  
Biological name :NACC2
  
Synonyms : NACC2 / NACC family member 2 / Q96BF6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.3
Gene start: 136006537
Gene end: 136095285
  
Corresponding Affymetrix probe sets: 212993_at (Human Genome U133 Plus 2.0 Array)   230050_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000277554
Ensembl peptide - ENSP00000360818
NCBI entrez gene - 138151     See in Manteia.
OMIM - 615786
RefSeq - NM_144653
RefSeq - XM_011518221
RefSeq Peptide - NP_653254
swissprot - A0A024R8I0
swissprot - Q96BF6
Ensembl - ENSG00000148411
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NACC2ENSGALG00000001728Gallus gallus
 Nacc2ENSMUSG00000026932Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NACC1 / Q96RE7 / nucleus accumbens associated 1ENSG0000016087749
O15209 / ZBTB22 / zinc finger and BTB domain containing 22ENSG0000023610418
O43298 / ZBTB43 / zinc finger and BTB domain containing 43ENSG0000016915515
Q5TC79 / ZBTB37 / zinc finger and BTB domain containing 37ENSG0000018527815
Q9HC78 / ZBTB20 / zinc finger and BTB domain containing 20ENSG0000018172214
Q8NCN2 / ZBTB34 / zinc finger and BTB domain containing 34ENSG0000017712514
Q96K62 / ZBTB45 / zinc finger and BTB domain containing 45ENSG0000011957413
ZBTB9 / Q96C00 / zinc finger and BTB domain containing 9ENSG0000021358813
Q9HCK0 / ZBTB26 / zinc finger and BTB domain containing 26ENSG0000017144812
ZBTB6 / Q15916 / zinc finger and BTB domain containing 6ENSG0000018613011
Q9Y330 / ZBTB12 / zinc finger and BTB domain containing 12ENSG0000020436610


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR018379  BEN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0010608 posttranscriptional regulation of gene expression IMP
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0034629 cellular protein-containing complex localization IDA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0051260 protein homooligomerization ISS
 biological_processGO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter IDA
 biological_processGO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage IDA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016581 NuRD complex IDA
 cellular_componentGO:0016604 nuclear body ISS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0004407 histone deacetylase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0042826 histone deacetylase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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