ENSMUSG00000026932


Mus musculus

Features
Gene ID: ENSMUSG00000026932
  
Biological name :Nacc2
  
Synonyms : Nacc2 / Nucleus accumbens-associated protein 2 / Q9DCM7
  
Possible biological names infered from orthology : NACC family member 2 / Q96BF6
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A3
Gene start: 26055535
Gene end: 26123220
  
Corresponding Affymetrix probe sets: 10480901 (MoGene1.0st)   1417152_at (Mouse Genome 430 2.0 Array)   1417153_at (Mouse Genome 430 2.0 Array)   1429582_at (Mouse Genome 430 2.0 Array)   1447608_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000028300
Ensembl peptide - ENSMUSP00000109796
Ensembl peptide - ENSMUSP00000120198
NCBI entrez gene - 67991     See in Manteia.
MGI - MGI:1915241
RefSeq - XM_006498260
RefSeq - NM_001037098
RefSeq - NM_026495
RefSeq - XM_006498259
RefSeq Peptide - NP_080771
RefSeq Peptide - NP_001032175
swissprot - Q9DCM7
swissprot - A2ARL3
Ensembl - ENSMUSG00000026932
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NACC2ENSGALG00000001728Gallus gallus
 NACC2ENSG00000148411Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nacc1 / Q7TSZ8 / Nucleus accumbens-associated protein 1 / Q96RE7* / nucleus accumbens associated 1*ENSMUSG0000000191049
Q9Z0G7 / Zbtb22 / zinc finger and BTB domain containing 22 / O15209*ENSMUSG0000005139018
Q9DAI4 / Zbtb43 / zinc finger and BTB domain containing 43 / O43298*ENSMUSG0000002678815
Zbtb37 / zinc finger and BTB domain containing 37 / Q5TC79*ENSMUSG0000004346715
Zbtb34 / zinc finger and BTB domain containing 34 / Q8NCN2*ENSMUSG0000006896614
Q8K0L9 / Zbtb20 / zinc finger and BTB domain containing 20 / Q9HC78*ENSMUSG0000002270814
Zbtb9 / Q8CDC7 / zinc finger and BTB domain containing 9 / Q96C00*ENSMUSG0000007960513
Q52KG4 / Zbtb45 / zinc finger and BTB domain containing 45 / Q96K62*ENSMUSG0000004960013
Zbtb26 / zinc finger and BTB domain containing 26 / Q9HCK0*ENSMUSG0000005071412
Zbtb6 / Q8K088 / zinc finger and BTB domain containing 6 / Q15916*ENSMUSG0000006679810
Zbtb12 / zinc finger and BTB domain containing 12 / Q9Y330*ENSMUSG0000004982310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR018379  BEN domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0010608 posttranscriptional regulation of gene expression ISO
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0034629 cellular protein-containing complex localization ISO
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0051260 protein homooligomerization ISO
 biological_processGO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter ISO
 biological_processGO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage ISO
 cellular_componentGO:0000790 nuclear chromatin ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0016581 NuRD complex ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001076 transcription factor activity, RNA polymerase II transcription factor binding ISO
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0004407 histone deacetylase activity ISO
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0042826 histone deacetylase binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000223 decreased monocyte count "fewer than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Nab2tm1b(EUCOMM)Hmgu/Nab2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nab2tm1b(EUCOMM)Hmgu/Ics

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
Show

Allelic Composition: Nab2tm1b(EUCOMM)Hmgu/Nab2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nab2tm1b(EUCOMM)Hmgu/Ics

 MP:0001510 abnormal coat appearance "coat that looks different from the usual state " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Nab2tm1b(EUCOMM)Hmgu/Nab2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nab2tm1b(EUCOMM)Hmgu/Ics

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Nab2tm1b(EUCOMM)Hmgu/Nab2tm1b(EUCOMM)Hmgu
Genetic Background: C57BL/6N-Nab2tm1b(EUCOMM)Hmgu/Ics

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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