ENSG00000148450


Homo sapiens

Features
Gene ID: ENSG00000148450
  
Biological name :MSRB2
  
Synonyms : methionine sulfoxide reductase B2 / MSRB2 / Q9Y3D2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: p12.2
Gene start: 23095506
Gene end: 23122013
  
Corresponding Affymetrix probe sets: 218773_s_at (Human Genome U133 Plus 2.0 Array)   219451_at (Human Genome U133 Plus 2.0 Array)   230575_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365693
Ensembl peptide - ENSP00000434990
NCBI entrez gene - 22921     See in Manteia.
OMIM - 613782
RefSeq - NM_012228
RefSeq Peptide - NP_036360
swissprot - Q9Y3D2
swissprot - H0YE51
Ensembl - ENSG00000148450
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 msrb2ENSDARG00000018459Danio rerio
 Msrb2ENSMUSG00000023094Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MSRB3 / Q8IXL7 / methionine sulfoxide reductase B3ENSG0000017409938


Protein motifs (from Interpro)
Interpro ID Name
 IPR002579  Peptide methionine sulphoxide reductase MrsB
 IPR011057  Mss4-like superfamily
 IPR028427  Peptide methionine sulfoxide reductase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0030041 actin filament polymerization IEA
 biological_processGO:0030091 protein repair IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor IEA
 molecular_functionGO:0033743 peptide-methionine (R)-S-oxide reductase activity IEA
 molecular_functionGO:0033745 L-methionine-(R)-S-oxide reductase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Protein repair


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136810 TXN / P10599 / thioredoxin  / reaction






 

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