ENSG00000148773


Homo sapiens

Features
Gene ID: ENSG00000148773
  
Biological name :MKI67
  
Synonyms : marker of proliferation Ki-67 / MKI67 / P46013
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q26.2
Gene start: 128096659
Gene end: 128126385
  
Corresponding Affymetrix probe sets: 212020_s_at (Human Genome U133 Plus 2.0 Array)   212021_s_at (Human Genome U133 Plus 2.0 Array)   212022_s_at (Human Genome U133 Plus 2.0 Array)   212023_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357642
Ensembl peptide - ENSP00000357643
NCBI entrez gene - 4288     See in Manteia.
OMIM - 176741
RefSeq - XM_011539818
RefSeq - NM_001145966
RefSeq - NM_002417
RefSeq Peptide - NP_002408
RefSeq Peptide - NP_001139438
swissprot - P46013
Ensembl - ENSG00000148773
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mki67ENSDARG00000091150Danio rerio
 ENSGALG00000025996Gallus gallus
 Mki67ENSMUSG00000031004Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR008984  SMAD/FHA domain superfamily
 IPR012568  KI67R
 IPR029334  Protein phosphatase 1 binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007088 regulation of mitotic nuclear division IDA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0051983 regulation of chromosome segregation IDA
 biological_processGO:1902275 regulation of chromatin organization ISS
 cellular_componentGO:0000793 condensed chromosome IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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