ENSMUSG00000031004


Mus musculus

Features
Gene ID: ENSMUSG00000031004
  
Biological name :Mki67
  
Synonyms : E9PVX6 / Mki67 / Proliferation marker protein Ki-67
  
Possible biological names infered from orthology : marker of proliferation Ki-67 / P46013
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: F3
Gene start: 135689784
Gene end: 135716361
  
Corresponding Affymetrix probe sets: 10568714 (MoGene1.0st)   1426817_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033310
Ensembl peptide - ENSMUSP00000147271
NCBI entrez gene - 17345     See in Manteia.
MGI - MGI:106035
RefSeq - XM_006507411
RefSeq - XM_006507413
RefSeq - NM_001081117
RefSeq - XM_006507412
RefSeq Peptide - NP_001074586
swissprot - E9PVX6
swissprot - A0A1B0GQV9
Ensembl - ENSMUSG00000031004
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mki67ENSDARG00000091150Danio rerio
 ENSGALG00000025996Gallus gallus
 MKI67ENSG00000148773Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR008984  SMAD/FHA domain superfamily
 IPR012568  KI67R
 IPR029334  Protein phosphatase 1 binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007088 regulation of mitotic nuclear division ISO
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0051321 meiotic cell cycle IDA
 biological_processGO:0051983 regulation of chromosome segregation ISO
 biological_processGO:0072574 hepatocyte proliferation IDA
 biological_processGO:1902275 regulation of chromatin organization IMP
 biological_processGO:1990705 cholangiocyte proliferation IDA
 cellular_componentGO:0000775 chromosome, centromeric region IDA
 cellular_componentGO:0000793 condensed chromosome ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0016604 nuclear body ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Igfbp7tm1.1Dds/Igfbp7+
Genetic Background: involves: CD-1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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