ENSG00000149557


Homo sapiens

Features
Gene ID: ENSG00000149557
  
Biological name :FEZ1
  
Synonyms : fasciculation and elongation protein zeta 1 / FEZ1 / Q99689
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q24.2
Gene start: 125445745
Gene end: 125496317
  
Corresponding Affymetrix probe sets: 203562_at (Human Genome U133 Plus 2.0 Array)   205973_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000278919
Ensembl peptide - ENSP00000431521
Ensembl peptide - ENSP00000434803
Ensembl peptide - ENSP00000463116
Ensembl peptide - ENSP00000393425
NCBI entrez gene - 9638     See in Manteia.
OMIM - 604825
RefSeq - XM_005271735
RefSeq - NM_005103
RefSeq - NM_022549
RefSeq - XM_005271734
RefSeq Peptide - NP_005094
RefSeq Peptide - NP_072043
swissprot - J3KTR6
swissprot - Q99689
swissprot - E9PNH2
Ensembl - ENSG00000149557
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fez1ENSDARG00000023174Danio rerio
 FEZ1ENSGALG00000038885Gallus gallus
 Fez1ENSMUSG00000032118Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FEZ2 / Q9UHY8 / fasciculation and elongation protein zeta 2ENSG0000017105546


Protein motifs (from Interpro)
Interpro ID Name
 IPR011680  Fasciculation and elongation protein zeta, FEZ
 IPR015642  Fasciculation and elongation protein zeta 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007411 axon guidance TAS
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0021766 hippocampus development IEA
 biological_processGO:0030010 establishment of cell polarity IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0051654 establishment of mitochondrion localization IEA
 biological_processGO:0061881 positive regulation of anterograde axonal transport of mitochondrion IEA
 biological_processGO:0070584 mitochondrion morphogenesis IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IEA
 biological_processGO:1902902 negative regulation of autophagosome assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030424 axon IBA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 molecular_functionGO:0005080 protein kinase C binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043015 gamma-tubulin binding IEA
 molecular_functionGO:0047485 protein N-terminus binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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