ENSG00000150938


Homo sapiens

Features
Gene ID: ENSG00000150938
  
Biological name :CRIM1
  
Synonyms : CRIM1 / cysteine rich transmembrane BMP regulator 1 / Q9NZV1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p22.2
Gene start: 36355926
Gene end: 36551135
  
Corresponding Affymetrix probe sets: 202551_s_at (Human Genome U133 Plus 2.0 Array)   202552_s_at (Human Genome U133 Plus 2.0 Array)   228496_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000280527
Ensembl peptide - ENSP00000403120
Ensembl peptide - ENSP00000407636
Ensembl peptide - ENSP00000415706
NCBI entrez gene - 51232     See in Manteia.
OMIM - 606189
RefSeq - XM_017004262
RefSeq - XM_011532901
RefSeq - XM_017004258
RefSeq - XM_017004259
RefSeq - XM_017004260
RefSeq - XM_017004261
RefSeq - NM_016441
RefSeq - XM_005264357
RefSeq - XM_011532898
RefSeq - XM_011532899
RefSeq Peptide - NP_057525
swissprot - H7C2T6
swissprot - H7C458
swissprot - H7C1Z0
swissprot - Q9NZV1
Ensembl - ENSG00000150938
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crim1ENSDARG00000029668Danio rerio
 CRIM1ENSGALG00000032640Gallus gallus
 Crim1ENSMUSG00000024074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCP / kielin/chordin-like proteinENSG0000013525321
VWCE / Q96DN2 / von Willebrand factor C and EGF domainsENSG0000016799217
BMPER / Q8N8U9 / BMP binding endothelial regulatorENSG000001646199


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR001007  VWFC domain
 IPR004094  Antistasin-like domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011061  Hirudin/antistatin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0048009 insulin-like growth factor receptor signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004857 enzyme inhibitor activity IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005010 insulin-like growth factor-activated receptor activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0030165 PDZ domain binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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