ENSG00000151320


Homo sapiens

Features
Gene ID: ENSG00000151320
  
Biological name :AKAP6
  
Synonyms : AKAP6 / A-kinase anchoring protein 6 / Q13023
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q12
Gene start: 32329273
Gene end: 32837681
  
Corresponding Affymetrix probe sets: 205359_at (Human Genome U133 Plus 2.0 Array)   217669_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000452204
Ensembl peptide - ENSP00000451247
Ensembl peptide - ENSP00000452109
Ensembl peptide - ENSP00000280979
Ensembl peptide - ENSP00000450531
Ensembl peptide - ENSP00000451146
Ensembl peptide - ENSP00000451239
Ensembl peptide - ENSP00000451246
NCBI entrez gene - 9472     See in Manteia.
OMIM - 604691
RefSeq - XM_017021810
RefSeq - NM_004274
RefSeq - XM_017021808
RefSeq - XM_017021809
RefSeq Peptide - NP_004265
swissprot - H0YJT7
swissprot - G3V3B5
swissprot - Q13023
swissprot - G3V3H2
swissprot - G3V3H6
swissprot - G3V569
swissprot - G3V3H7
Ensembl - ENSG00000151320
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 akap6ENSDARG00000077295Danio rerio
 AKAP6ENSGALG00000009995Gallus gallus
 Akap6ENSMUSG00000061603Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CEP68 / Q76N32 / centrosomal protein 68ENSG000000115235


Protein motifs (from Interpro)
Interpro ID Name
 IPR002017  Spectrin repeat
 IPR018159  Spectrin/alpha-actinin
 IPR026696  A-kinase anchor protein 6/Centrosomal protein of 68kDa


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IC
 biological_processGO:0006605 protein targeting NAS
 biological_processGO:0010738 regulation of protein kinase A signaling ISS
 biological_processGO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum IC
 biological_processGO:0019933 cAMP-mediated signaling NAS
 biological_processGO:0030307 positive regulation of cell growth ISS
 biological_processGO:0032516 positive regulation of phosphoprotein phosphatase activity ISS
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol ISS
 biological_processGO:0060306 regulation of membrane repolarization IDA
 biological_processGO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity ISS
 biological_processGO:0061051 positive regulation of cell growth involved in cardiac muscle cell development ISS
 biological_processGO:0070886 positive regulation of calcineurin-NFAT signaling cascade ISS
 biological_processGO:0071320 cellular response to cAMP IDA
 biological_processGO:0071345 cellular response to cytokine stimulus ISS
 biological_processGO:1901381 positive regulation of potassium ion transmembrane transport IDA
 biological_processGO:1902261 positive regulation of delayed rectifier potassium channel activity IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005635 nuclear envelope IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005901 caveola ISS
 cellular_componentGO:0014701 junctional sarcoplasmic reticulum membrane ISS
 cellular_componentGO:0014704 intercalated disc ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016529 sarcoplasmic reticulum IEA
 cellular_componentGO:0030315 T-tubule ISS
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0034704 calcium channel complex IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008179 adenylate cyclase binding ISS
 molecular_functionGO:0032947 protein-containing complex scaffold activity ISS
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding ISS
 molecular_functionGO:0043495 protein membrane anchor ISS
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:0051018 protein kinase A binding TAS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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