ENSG00000151725


Homo sapiens

Features
Gene ID: ENSG00000151725
  
Biological name :CENPU
  
Synonyms : CENPU / centromere protein U / Q71F23
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q35.1
Gene start: 184694618
Gene end: 184734133
  
Corresponding Affymetrix probe sets: 218883_s_at (Human Genome U133 Plus 2.0 Array)   229304_s_at (Human Genome U133 Plus 2.0 Array)   229305_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423167
Ensembl peptide - ENSP00000423248
Ensembl peptide - ENSP00000281453
NCBI entrez gene - 79682     See in Manteia.
OMIM - 611511
RefSeq - NM_024629
RefSeq - XM_005263218
RefSeq Peptide - NP_078905
swissprot - D6R9S4
swissprot - Q09GN1
swissprot - Q71F23
Ensembl - ENSG00000151725
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-185e18.7ENSDARG00000088924Danio rerio
 CENPUENSGALG00000020210Gallus gallus
 CenpuENSMUSG00000031629Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR025214  Centromere protein U


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0034080 CENP-A containing nucleosome assembly TAS
 biological_processGO:0043009 chordate embryonic development IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Deposition of new CENPA-containing nucleosomes at the centromere
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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