ENSG00000152944


Homo sapiens

Features
Gene ID: ENSG00000152944
  
Biological name :MED21
  
Synonyms : MED21 / mediator complex subunit 21 / Q13503
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p11.23
Gene start: 27022546
Gene end: 27066343
  
Corresponding Affymetrix probe sets: 209362_at (Human Genome U133 Plus 2.0 Array)   209363_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444297
Ensembl peptide - ENSP00000282892
Ensembl peptide - ENSP00000442126
NCBI entrez gene - 9412     See in Manteia.
OMIM - 603800
RefSeq - NM_001271811
RefSeq - NM_004264
RefSeq Peptide - NP_001258740
RefSeq Peptide - NP_004255
swissprot - Q13503
swissprot - A0A024RAW0
swissprot - F5GZQ1
swissprot - F5H872
Ensembl - ENSG00000152944
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med21ENSDARG00000026839Danio rerio
 MED21ENSGALG00000027435Gallus gallus
 Med21ENSMUSG00000030291Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021384  Mediator complex, subunit Med21
 IPR037212  Mediator complex, subunit Med7/Med21-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001824 blastocyst development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II TAS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IDA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016592 mediator complex IDA
 molecular_functionGO:0003713 transcription coactivator activity IDA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
PPARA activates gene expression
Transcriptional regulation of white adipocyte differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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