ENSMUSG00000030291


Mus musculus

Features
Gene ID: ENSMUSG00000030291
  
Biological name :Med21
  
Synonyms : Med21 / Mediator of RNA polymerase II transcription subunit 21 / Q9CQ39
  
Possible biological names infered from orthology : mediator complex subunit 21 / Q13503
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: G3
Gene start: 146642547
Gene end: 146650732
  
Corresponding Affymetrix probe sets: 10542750 (MoGene1.0st)   1425806_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000107277
Ensembl peptide - ENSMUSP00000145512
Ensembl peptide - ENSMUSP00000032429
NCBI entrez gene - 108098     See in Manteia.
MGI - MGI:1347064
RefSeq - NM_025315
RefSeq Peptide - NP_079591
swissprot - B2KG29
swissprot - Q9CQ39
Ensembl - ENSMUSG00000030291
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 med21ENSDARG00000026839Danio rerio
 MED21ENSGALG00000027435Gallus gallus
 MED21ENSG00000152944Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR021384  Mediator complex, subunit Med21
 IPR037212  Mediator complex, subunit Med7/Med21-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001824 blastocyst development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IC
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0019827 stem cell population maintenance IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0016592 mediator complex ISO
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
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Allelic Composition: Actbtm1(PyVT)Arge/Actb+,Waptm1(cre)Arge/Wap+
Genetic Background: involves: 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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