ENSG00000153086


Homo sapiens

Features
Gene ID: ENSG00000153086
  
Biological name :ACMSD
  
Synonyms : ACMSD / aminocarboxymuconate semialdehyde decarboxylase / Q8TDX5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q21.3
Gene start: 134838547
Gene end: 134902034
  
Corresponding Affymetrix probe sets: 230602_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000376659
Ensembl peptide - ENSP00000348459
NCBI entrez gene - 130013     See in Manteia.
OMIM - 608889
RefSeq - XM_017003326
RefSeq - NM_001307983
RefSeq - NM_138326
RefSeq - XM_005263589
RefSeq - XM_005263590
RefSeq - XM_011510592
RefSeq - XM_017003325
RefSeq - XM_005263586
RefSeq - XM_005263588
RefSeq Peptide - NP_001294912
RefSeq Peptide - NP_612199
swissprot - Q8TDX5
swissprot - A0A0S2Z681
Ensembl - ENSG00000153086
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acmsdENSDARG00000062549Danio rerio
 ACMSDENSGALG00000012197Gallus gallus
 AcmsdENSMUSG00000026348Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006680  Amidohydrolase-related
 IPR032465  2-amino-3-carboxymuconate-6-semialdehyde decarboxylase
 IPR032466  Metal-dependent hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006569 tryptophan catabolic process TAS
 biological_processGO:0051259 protein complex oligomerization IDA
 biological_processGO:1904985 negative regulation of quinolinate biosynthetic process IDA
 biological_processGO:1905004 picolinic acid biosynthetic process TAS
 biological_processGO:1905012 regulation of "de novo" NAD biosynthetic process from tryptophan TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001760 aminocarboxymuconate-semialdehyde decarboxylase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0016831 carboxy-lyase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000153086 ACMSD / Q8TDX5 / aminocarboxymuconate semialdehyde decarboxylase  / complex






 

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