ENSG00000153404


Homo sapiens

Features
Gene ID: ENSG00000153404
  
Biological name :PLEKHG4B
  
Synonyms : pleckstrin homology and RhoGEF domain containing G4B / PLEKHG4B / Q96PX9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p15.33
Gene start: 92151
Gene end: 189972
  
Corresponding Affymetrix probe sets: 230441_at (Human Genome U133 Plus 2.0 Array)   236255_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000490806
Ensembl peptide - ENSP00000283426
Ensembl peptide - ENSP00000422493
NCBI entrez gene - 153478     See in Manteia.
RefSeq - XM_017009112
RefSeq - NM_052909
RefSeq - XM_011513970
RefSeq - XM_011513971
RefSeq - XM_011513972
RefSeq - XM_011513973
RefSeq - XM_006714446
RefSeq - XM_011513968
RefSeq - XM_011513969
RefSeq Peptide - NP_443141
swissprot - Q96HN1
swissprot - Q96PX9
swissprot - A0A1B0GW72
Ensembl - ENSG00000153404
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q58EX7 / PLEKHG4 / pleckstrin homology and RhoGEF domain containing G4ENSG0000019615530
Q8TER5 / ARHGEF40 / Rho guanine nucleotide exchange factor 40ENSG0000016580124
Q5JYT7 / KIAA1755ENSG0000014963315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily
 IPR036865  CRAL-TRIO lipid binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr