ENSG00000165801


Homo sapiens

Features
Gene ID: ENSG00000165801
  
Biological name :ARHGEF40
  
Synonyms : ARHGEF40 / Q8TER5 / Rho guanine nucleotide exchange factor 40
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q11.2
Gene start: 21070270
Gene end: 21090240
  
Corresponding Affymetrix probe sets: 220326_s_at (Human Genome U133 Plus 2.0 Array)   227855_at (Human Genome U133 Plus 2.0 Array)   237954_x_at (Human Genome U133 Plus 2.0 Array)   241627_x_at (Human Genome U133 Plus 2.0 Array)   241631_at (Human Genome U133 Plus 2.0 Array)   58780_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000298694
Ensembl peptide - ENSP00000451335
Ensembl peptide - ENSP00000451655
Ensembl peptide - ENSP00000452283
NCBI entrez gene - 55701     See in Manteia.
OMIM - 610018
RefSeq - XM_017021437
RefSeq - NM_001278530
RefSeq - NM_018071
RefSeq - XM_005267844
RefSeq - XM_011536937
RefSeq - XM_017021434
RefSeq - XM_017021435
RefSeq - XM_017021436
RefSeq - NM_001278529
RefSeq Peptide - NP_060541
RefSeq Peptide - NP_001265458
RefSeq Peptide - NP_001265459
swissprot - G3V3N2
swissprot - Q8TER5
swissprot - G3V5C1
swissprot - G3V485
Ensembl - ENSG00000165801
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef40ENSDARG00000078979Danio rerio
 Q3UPH7ENSMUSG00000004562Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q58EX7 / PLEKHG4 / pleckstrin homology and RhoGEF domain containing G4ENSG0000019615522
Q96PX9 / PLEKHG4B / pleckstrin homology and RhoGEF domain containing G4BENSG0000015340420
Q5JYT7 / KIAA1755ENSG0000014963318


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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