ENSMUSG00000004562


Mus musculus

Features
Gene ID: ENSMUSG00000004562
  
Biological name :Arhgef40
  
Synonyms : Arhgef40 / Q3UPH7 / Rho guanine nucleotide exchange factor 40
  
Possible biological names infered from orthology : Q8TER5
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C2
Gene start: 51984719
Gene end: 52006251
  
Corresponding Affymetrix probe sets: 10414623 (MoGene1.0st)   1436768_x_at (Mouse Genome 430 2.0 Array)   1438485_at (Mouse Genome 430 2.0 Array)   1442768_at (Mouse Genome 430 2.0 Array)   1455810_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000091331
Ensembl peptide - ENSMUSP00000098204
Ensembl peptide - ENSMUSP00000138125
Ensembl peptide - ENSMUSP00000138751
Ensembl peptide - ENSMUSP00000138797
Ensembl peptide - ENSMUSP00000138128
Ensembl peptide - ENSMUSP00000138339
Ensembl peptide - ENSMUSP00000138354
Ensembl peptide - ENSMUSP00000138405
Ensembl peptide - ENSMUSP00000138424
Ensembl peptide - ENSMUSP00000138482
Ensembl peptide - ENSMUSP00000138568
Ensembl peptide - ENSMUSP00000138635
Ensembl peptide - ENSMUSP00000138638
NCBI entrez gene - 268739     See in Manteia.
MGI - MGI:2685515
RefSeq - XM_017316026
RefSeq - NM_001145921
RefSeq - NM_001145922
RefSeq - NM_198249
RefSeq - XM_006519041
RefSeq - XM_006519042
RefSeq - XM_006519044
RefSeq - XM_006519045
RefSeq - XM_006519046
RefSeq - XM_011245076
RefSeq Peptide - NP_001139394
RefSeq Peptide - NP_937892
RefSeq Peptide - NP_001139393
swissprot - S4R2A6
swissprot - S4R2G8
swissprot - S4R2R3
swissprot - S4R2U9
swissprot - Q3UPH7
swissprot - S4R189
swissprot - S4R1R5
swissprot - S4R1X0
swissprot - S4R1S6
swissprot - S4R1Y4
swissprot - S4R237
Ensembl - ENSMUSG00000004562
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef40ENSDARG00000078979Danio rerio
 Q8TER5ENSG00000165801Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plekhg4 / pleckstrin homology and RhoGEF domain containing G4 / Q58EX7*ENSMUSG0000001478221
Q8BWG4 / D630003M21Rik / Uncharacterized / Q5JYT7* / KIAA1755*ENSMUSG0000003781317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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