ENSG00000153721


Homo sapiens

Features
Gene ID: ENSG00000153721
  
Biological name :CNKSR3
  
Synonyms : CNKSR3 / CNKSR family member 3 / Q6P9H4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q25.2
Gene start: 154387504
Gene end: 154510659
  
Corresponding Affymetrix probe sets: 1569331_at (Human Genome U133 Plus 2.0 Array)   227481_at (Human Genome U133 Plus 2.0 Array)   237302_at (Human Genome U133 Plus 2.0 Array)   242394_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000393225
Ensembl peptide - ENSP00000418975
Ensembl peptide - ENSP00000475915
NCBI entrez gene - 154043     See in Manteia.
OMIM - 617476
RefSeq - XM_011535485
RefSeq - NM_173515
RefSeq Peptide - NP_775786
swissprot - Q5T4Y8
swissprot - Q6P9H4
Ensembl - ENSG00000153721
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnksr3ENSDARG00000105277Danio rerio
 ipcef1ENSDARG00000099252Danio rerio
 ENSGALG00000027159Gallus gallus
 ENSGALG00000013625Gallus gallus
 Ipcef1ENSMUSG00000064065Mus musculus
 Magi1ENSMUSG00000015202Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CNKSR2 / Q8WXI2 / connector enhancer of kinase suppressor of Ras 2ENSG0000014997056
CNKSR1 / Q969H4 / connector enhancer of kinase suppressor of Ras 1ENSG0000014267525
IPCEF1 / Q8WWN9 / interaction protein for cytohesin exchange factors 1ENSG000000747063


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001660  Sterile alpha motif domain
 IPR010599  Connector enhancer of kinase suppressor of ras 2
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR017874  CRIC domain
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0010765 positive regulation of sodium ion transport ISS
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation ISS
 biological_processGO:0070373 negative regulation of ERK1 and ERK2 cascade ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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